Accès gratuit
Numéro
Med Sci (Paris)
Volume 28, Numéro 1, Janvier 2012
Page(s) 96 - 102
Section M/S Revues
DOI https://doi.org/10.1051/medsci/2012281023
Publié en ligne 27 janvier 2012
  1. Medzhitov R. Approaching the asymptote: 20 years later. Immunity 2009 ; 30 : 766–775. [CrossRef] [PubMed] [Google Scholar]
  2. Blasius AL, Beutler B. Intracellular Toll-like receptors. Immunity 2010 ; 32 : 305–315. [CrossRef] [PubMed] [Google Scholar]
  3. Kawai T, Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 2011 ; 34 : 637–650. [CrossRef] [PubMed] [Google Scholar]
  4. Delneste Y, Beauvillain C, Jeannin P. Immunité naturelle : structure et fonction des Toll-like receptors. Med Sci (Paris) 2007 ; 23 : 67–73. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  5. Chatenoud L. Immunité innée et immunité adaptative : un flirt bénéfique ? Med Sci (Paris) 2002 ; 18 : 1183–1184. [CrossRef] [EDP Sciences] [Google Scholar]
  6. Leulier F, Lemaitre B. Toll-like receptors: taking an evolutionary approach. Nat Rev Genet 2008 ; 9 : 165–178. [CrossRef] [PubMed] [Google Scholar]
  7. Medzhitov R, Preston-Hurlburt P, Janeway CAJr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997 ; 388 : 394–397. [CrossRef] [PubMed] [Google Scholar]
  8. Yu L, Wang L, Chen S. Endogenous Toll-like receptor ligands and their biological significance. J Cell Mol Med 2010 ; 14 : 2592–2603. [CrossRef] [PubMed] [Google Scholar]
  9. Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 2001 ; 413 : 732–738. [CrossRef] [PubMed] [Google Scholar]
  10. Zhang SY, Jouanguy E, Ugolini S, et al. TLR3 deficiency in patients with herpes simplex encephalitis. Science 2007 ; 317 : 1522–1527. [CrossRef] [PubMed] [Google Scholar]
  11. Heil F, Hemmi H, Hochrein H, et al. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 2004 ; 303 : 1526–1529. [CrossRef] [PubMed] [Google Scholar]
  12. Kawai T, Akira S. Innate immune recognition of viral infection. Nat Immunol 2006 ; 7 : 131–137. [CrossRef] [PubMed] [Google Scholar]
  13. Mancuso G, Gambuzza M, Midiri A, et al. Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells. Nat Immunol 2009 ; 10 : 587–594. [CrossRef] [PubMed] [Google Scholar]
  14. Martinez J, Huang X, Yang Y. Toll-like receptor 8-mediated activation of murine plasmacytoid dendritic cells by vaccinia viral DNA. Proc Natl Acad Sci USA 2010 ; 107 : 6442–6447. [CrossRef] [Google Scholar]
  15. Bauer S, Bathke B, Lauterbach H, et al. A major role for TLR8 in the recognition of vaccinia viral DNA by murine pDC? Proc Natl Acad Sci USA 2010 ; 107 : E139. 40. [CrossRef] [Google Scholar]
  16. Krieg AM, Love-Homan L, Yi AK, Harty JT. CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge. J Immunol 1998 ; 161 : 2428–2434. [PubMed] [Google Scholar]
  17. Zimmermann S, Egeter O, Hausmann S, et al. CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis. J Immunol 1998 ; 160 : 3627–3630. [PubMed] [Google Scholar]
  18. Barton GM, Kagan JC, Medzhitov R. Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA. Nat Immunol 2006 ; 7 : 49–56. [CrossRef] [PubMed] [Google Scholar]
  19. Tabeta K, Hoebe K, Janssen EM, et al. The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol 2006 ; 7 : 156–164. [CrossRef] [PubMed] [Google Scholar]
  20. Ewald SE, Engel A, Lee J, et al. Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase. J Exp Med 2011 ; 208 : 643–651. [CrossRef] [PubMed] [Google Scholar]
  21. Sepulveda FE, Maschalidi S, Colisson R, et al. Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells. Immunity 2009 ; 31 : 737–748. [CrossRef] [PubMed] [Google Scholar]
  22. Demaria O, Pagni PP, Traub S, et al. TLR8 deficiency leads to autoimmunity in mice. J Clin Invest 2010 ; 120 : 3651–3662. [PubMed] [Google Scholar]
  23. Richez C, Blanco P, Rifkin I, et al. Role for Toll-like receptors in autoimmune disease: the example of systemic lupus erythematosus. Joint Bone Spine 2011 ; 78 : 124–130. [CrossRef] [PubMed] [Google Scholar]
  24. Wang J, Shao Y, Bennett TA, et al. The functional effects of physical interactions among Toll-like receptors 7, 8, and 9. J Biol Chem 2006 ; 281 : 37427–37434. [CrossRef] [PubMed] [Google Scholar]
  25. Fukui R, Saitoh S, Matsumoto F, et al. Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing. J Exp Med 2009 ; 206 : 1339–1350. [CrossRef] [PubMed] [Google Scholar]
  26. Crozat K, Vivier E, Dalod M. Crosstalk between components of the innate immune system: promoting anti-microbial defenses and avoiding immunopathologies. Immunol Rev 2009 ; 227 : 129–149. [CrossRef] [PubMed] [Google Scholar]
  27. Gorden KB, Gorski KS, Gibson SJ, et al. Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8. J Immunol 2005 ; 174 : 1259–1268. [CrossRef] [PubMed] [Google Scholar]
  28. Schon MP, Schon M. TLR7 and TLR8 as targets in cancer therapy. Oncogene 2008 ; 27 : 190–199. [CrossRef] [PubMed] [Google Scholar]
  29. Stanley MA. Imiquimod and the imidazoquinolones: mechanism of action and therapeutic potential. Clin Exp Dermatol 2002 ; 27 : 571–577. [CrossRef] [PubMed] [Google Scholar]
  30. Zagon IS, Donahue RN, Rogosnitzky M, McLaughlin PJ. Imiquimod upregulates the opioid growth factor receptor to inhibit cell proliferation independent of immune function. Exp Biol Med (Maywood) 2008 ; 233 : 968–979. [CrossRef] [PubMed] [Google Scholar]
  31. Krieg AM, Vollmer J. Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity. Immunol Rev 2007 ; 220 : 251–269. [CrossRef] [PubMed] [Google Scholar]
  32. Vollmer J, Tluk S, Schmitz C, et al. Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8. J Exp Med 2005 ; 202 : 1575–1585. [CrossRef] [PubMed] [Google Scholar]
  33. Sacre SM, Lo A, Gregory B, et al. Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures. J Immunol 2008 ; 181 : 8002–8009. [PubMed] [Google Scholar]
  34. Saruta M, Targan SR, Mei L, et al. High-frequency haplotypes in the X chromosome locus TLR8 are associated with both CD and UC in females. Inflamm Bowel Dis 2009 ; 15 : 321–327. [CrossRef] [PubMed] [Google Scholar]
  35. Zhang P, Cox CJ, Alvarez KM, Cunningham MW. Cutting edge: cardiac myosin activates innate immune responses through TLRs. J Immunol 2009 ; 183 : 27–31. [CrossRef] [PubMed] [Google Scholar]
  36. Gringhuis SI, van der Vlist M, van den Berg LM, et al. HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells. Nat Immunol 2010 ; 11 : 419–426. [CrossRef] [PubMed] [Google Scholar]
  37. Hennessy EJ, Parker AE, O’Neill LA. Targeting Toll-like receptors: emerging therapeutics? Nat Rev Drug Discov 2010 ; 9 : 293–307. [CrossRef] [PubMed] [Google Scholar]
  38. Levy O, Suter EE, Miller RL, Wessels MR. Unique efficacy of Toll-like receptor 8 agonists in activating human neonatal antigen-presenting cells. Blood 2006 ; 108 : 1284–1290. [CrossRef] [PubMed] [Google Scholar]
  39. Imler JL, Ferrandon D. Le printemps de l’immunité innée couronné à Stockholm. Prix Nobel de médecine 2011. Med Sci (Paris) 2011 ; 27 : 1019–1024. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  40. Lanteri MC, Diamond MS, Norris PJ, Busch MP. Infection par le virus West Nile chez l’homme. II. Aspects physiopathologiques et réponses immunitaires. Med Sci (Paris) 2011 ; 27 : 382–386. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]

Les statistiques affichées correspondent au cumul d'une part des vues des résumés de l'article et d'autre part des vues et téléchargements de l'article plein-texte (PDF, Full-HTML, ePub... selon les formats disponibles) sur la platefome Vision4Press.

Les statistiques sont disponibles avec un délai de 48 à 96 heures et sont mises à jour quotidiennement en semaine.

Le chargement des statistiques peut être long.