Des cellules souches embryonnaires humaines pour la thérapie cellulaire de la maladie de Huntington

Laetitia Aubry; Marc Peschanski; Anselme L. Perrier

doi:10.1051/medsci/2009254333

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Volume 25 / Numéro 4 (Avril 2009)

Med Sci (Paris), 25 4 (2009) 333-335

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Numéro		Med Sci (Paris) Volume 25, Numéro 4, Avril 2009


Page(s)		333 - 335
Section		Nouvelles
DOI		https://doi.org/10.1051/medsci/2009254333
Publié en ligne		15 avril 2009

Bachoud-Levi AC, Remy P, Nguyen JP, et al. Motor and cognitive improvements in patients with Huntington’s disease after neural transplantation. Lancet 2000; 356 : 1975–9. [Google Scholar]
Bachoud-Levi AC, Gaura V, Brugieres P, et al. Effect of fetal neural transplants in patients with Huntington’s disease 6 years after surgery: a long-term follow-up study. Lancet Neurol 2006; 5 : 303–9. [Google Scholar]
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Aubry L, Bugi A, Lefort N, et al. Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats. Proc Natl Acad Sci USA 2008; 105 : 16707–12. [Google Scholar]
Perrier AL, Tabar V, Barberi T, et al. Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc Natl Acad Sci USA 2004; 101 :12543–8. [Google Scholar]
Ericson J, Muhr J, Placzek M, et al. Sonic hedgehog induces the differentiation of ventral forebrain neurons: a common signal for ventral patterning within the neural tube. Cell 1995; 81 : 747–56. [Google Scholar]
Backman MM, Machon O, Mygland L, et al. Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon. Dev Biol 2005; 279 : 155–68. [Google Scholar]
Watanabe K, Kamiya D, Nishiyama T, et al. Directed differentiation of telencephalic precursors from embryonic stem cells. Nat Neurosci 2005; 8 : 288–96. [Google Scholar]
Fluckiger AC, Dehay C, Savatier P. Cellules souches embryonnaires et thérapies cellulaires du système nerveux. Med Sci (Paris) 2003; 19 : 699–708. [Google Scholar]

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[1] Bachoud-Levi AC, Remy P, Nguyen JP, et al. Motor and cognitive improvements in patients with Huntington’s disease after neural transplantation. Lancet 2000; 356 : 1975–9. [Google Scholar]

[2] Bachoud-Levi AC, Gaura V, Brugieres P, et al. Effect of fetal neural transplants in patients with Huntington’s disease 6 years after surgery: a long-term follow-up study. Lancet Neurol 2006; 5 : 303–9. [Google Scholar]

[3] Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science 1998; 282 : 1145–7. [Google Scholar]

[4] Aubry L, Bugi A, Lefort N, et al. Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats. Proc Natl Acad Sci USA 2008; 105 : 16707–12. [Google Scholar]

[5] Perrier AL, Tabar V, Barberi T, et al. Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc Natl Acad Sci USA 2004; 101 :12543–8. [Google Scholar]

[6] Ericson J, Muhr J, Placzek M, et al. Sonic hedgehog induces the differentiation of ventral forebrain neurons: a common signal for ventral patterning within the neural tube. Cell 1995; 81 : 747–56. [Google Scholar]

[7] Backman MM, Machon O, Mygland L, et al. Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon. Dev Biol 2005; 279 : 155–68. [Google Scholar]

[8] Watanabe K, Kamiya D, Nishiyama T, et al. Directed differentiation of telencephalic precursors from embryonic stem cells. Nat Neurosci 2005; 8 : 288–96. [Google Scholar]

[9] Fluckiger AC, Dehay C, Savatier P. Cellules souches embryonnaires et thérapies cellulaires du système nerveux. Med Sci (Paris) 2003; 19 : 699–708. [Google Scholar]