Un neuropeptide à l’origine du vieillissement testiculaire ?

Arnaud Lacombe; Vincent Lelièvre; Charles E. Roselli; Wael Salameh; Yan-He Lue; Gregory Lawson; Jean-Marc Muller; James A. Waschek; Éric Vilain

doi:10.1051/medsci/20062210809

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Volume 22 / Numéro 10 (Octobre 2006)

Med Sci (Paris), 22 10 (2006) 809-811

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Numéro		Med Sci (Paris) Volume 22, Numéro 10, Octobre 2006


Page(s)		809 - 811
Section		Nouvelles
DOI		https://doi.org/10.1051/medsci/20062210809
Publié en ligne		15 octobre 2006

Hijazi RA, Cunningham GR. Andropause : is androgen replacement therapy indicated for the aging male ? Annu Rev Med 2005; 56 : 117–37. [Google Scholar]
Sternbach H. Age-associated testosterone decline in men: clinical issues for psychiatry. Am J Psychiatry 1998; 155 : 1310–8. [Google Scholar]
Gosden RG, Richardson DW, Brown N, Davidson DW. Structure and gametogenic potential of seminiferous tubules in ageing mice. J Reprod Fertil 1982; 64 : 127–33. [Google Scholar]
Wang C, Hikim AS, Ferrini M, et al. Male reproductive ageing: using the brown Norway rat as a model for man. Novartis Found Symp 2002; 242 : 82–97. [Google Scholar]
Peltola V, Huhtaniemi I, Metsa-Ketela T, Ahotupa M. Induction of lipid peroxidation during steroidogenesis in the rat testis. Endocrinology 1996; 137 : 105–12. [Google Scholar]
Quinn PG, Payne AH. Steroid product-induced, oxygen-mediated damage of microsomal cytochrome P-450 enzymes in Leydig cell cultures. Relationship to desensitization. J Biol Chem 1985; 260 : 2092–9. [Google Scholar]
Chen H, Hardy MP, Huhtaniemi I, Zirkin BR. Age-related decreased Leydig cell testosterone production in the brown Norway rat. J Androl 1994; 15 : 551–7. [Google Scholar]
Chen H, Huhtaniemi I, Zirkin BR. Depletion and repopulation of Leydig cells in the testes of aging brown Norway rats. Endocrinology 1996; 137 : 3447–52. [Google Scholar]
Arimura A, Somogyvari-Vigh A, Miyata A, et al. Tissue distribution of PACAP as determined by RIA: highly abundant in the rat brain and testes. Endocrinology 1991; 129 : 2787–9. [Google Scholar]
Lacombe A, Lelievre V, Roselli CE, et al. Delayed testicular aging in pituitary adenylate cyclase-activating peptide (PACAP) null mice. Proc Natl Acad Sci USA 2006; 103 : 3793–8. [Google Scholar]

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[1] Hijazi RA, Cunningham GR. Andropause : is androgen replacement therapy indicated for the aging male ? Annu Rev Med 2005; 56 : 117–37. [Google Scholar]

[2] Sternbach H. Age-associated testosterone decline in men: clinical issues for psychiatry. Am J Psychiatry 1998; 155 : 1310–8. [Google Scholar]

[3] Gosden RG, Richardson DW, Brown N, Davidson DW. Structure and gametogenic potential of seminiferous tubules in ageing mice. J Reprod Fertil 1982; 64 : 127–33. [Google Scholar]

[4] Wang C, Hikim AS, Ferrini M, et al. Male reproductive ageing: using the brown Norway rat as a model for man. Novartis Found Symp 2002; 242 : 82–97. [Google Scholar]

[5] Peltola V, Huhtaniemi I, Metsa-Ketela T, Ahotupa M. Induction of lipid peroxidation during steroidogenesis in the rat testis. Endocrinology 1996; 137 : 105–12. [Google Scholar]

[6] Quinn PG, Payne AH. Steroid product-induced, oxygen-mediated damage of microsomal cytochrome P-450 enzymes in Leydig cell cultures. Relationship to desensitization. J Biol Chem 1985; 260 : 2092–9. [Google Scholar]

[7] Chen H, Hardy MP, Huhtaniemi I, Zirkin BR. Age-related decreased Leydig cell testosterone production in the brown Norway rat. J Androl 1994; 15 : 551–7. [Google Scholar]

[8] Chen H, Huhtaniemi I, Zirkin BR. Depletion and repopulation of Leydig cells in the testes of aging brown Norway rats. Endocrinology 1996; 137 : 3447–52. [Google Scholar]

[9] Arimura A, Somogyvari-Vigh A, Miyata A, et al. Tissue distribution of PACAP as determined by RIA: highly abundant in the rat brain and testes. Endocrinology 1991; 129 : 2787–9. [Google Scholar]

[10] Lacombe A, Lelievre V, Roselli CE, et al. Delayed testicular aging in pituitary adenylate cyclase-activating peptide (PACAP) null mice. Proc Natl Acad Sci USA 2006; 103 : 3793–8. [Google Scholar]