Accès gratuit
Numéro
Med Sci (Paris)
Volume 21, Numéro 5, Mai 2005
Page(s) 484 - 490
Section M/S revues
DOI https://doi.org/10.1051/medsci/2005215484
Publié en ligne 15 mai 2005
  1. Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981; 292 : 154–6.
  2. Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci USA 1981; 78 : 7634–8.
  3. Gerecht-Nir S, Itskovitz-Eldor J. Cell therapy using human embryonic stem cells. Transpl Immunol 2004; 12 : 203–9.
  4. Fluckiger AC, Dehay C, Savatier P. Embryonic stem cells and cell replacement therapies in the nervous system. Med Sci (Paris) 2003; 19 : 699–708.
  5. McKay RD. Stem cell biology and neurodegenerative disease. Philos Trans R Soc Lond B Biol Sci 2004; 359 : 851–6.
  6. Takeda K, Noguchi K, Shi W, et al. Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc Natl Acad Sci USA 1997; 94 : 3801–4.
  7. Li M, Sendtner M, Smith A. Essential function of LIF receptor in motor neurons. Nature 1995; 378 : 724–7.
  8. Stewart CL, Kaspar P, Brunet LJ, et al. Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor. Nature 1992; 359 : 76–9.
  9. O’Shea KS. Self-renewal versus differentiation of mouse embryonic stem cells. Biol Reprod 2004; 71 : 1755–65.
  10. Nichols J. Introducing embryonic stem cells. Curr Biol 2001; 11 : R503–5.
  11. Mitsui K, Tokuzawa Y, Itoh H, et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003; 113 : 631–42.
  12. Niwa H. Molecular mechanism to maintain stem cell renewal of ES cells. Cell Struct Funct 2001; 26 : 137–48.
  13. Nichols J, Zevnik B, Anastassiadis K, et al. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 1998; 95 : 379–91.
  14. Hatano SY, Tada M, Kimura H, et al. Pluripotential competence of cells associated with Nanog activity. Mech Dev 2005; 122 : 67–79.
  15. Shimozaki K, Nakashima K, Niwa H, et al. Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis-inducing cultures. Development 2003; 130 : 2505–12.
  16. Panchision DM, McKay RD. The control of neural stem cells by morphogenic signals. Curr Opin Genet Dev 2002; 12 : 478–87.
  17. Jessell TM. Neuronal specification in the spinal cord : inductive signals and transcriptional codes. Nat Rev Genet 2000; 1 : 20–9.
  18. Wilson SI, Edlund T. Neural induction : toward a unifying mechanism. Nat Neurosci 2001; 4 (suppl) : 1161–8.
  19. Tropepe V, Hitoshi S, Sirard C, et al. Direct neural fate specification from embryonic stem cells : a primitive mammalian neural stem cell stage acquired through a default mechanism. Neuron 2001; 30 : 65–78.
  20. Czyz J, Wobus A. Embryonic stem cell differentiation : the role of extracellular factors. Differentiation 2001; 68 : 167–74.
  21. Coucouvanis E, Martin GR. BMP signaling plays a role in visceral endoderm differentiation and cavitation in the early mouse embryo. Development 1999; 126 : 535–46.
  22. Aubert J, Dunstan H, Chambers I, et al. Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation. Nat Biotechnol 2002; 20 : 1240–5.
  23. Kielman MF, Rindapaa M, Gaspar C, et al. Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling. Nat Genet 2002; 32 : 594–605.
  24. Otero JJ, Fu W, Kan L, et al. Beta-catenin signaling is required for neural differentiation of embryonic stem cells. Development 2004; 131 : 3545–57.
  25. Ying QL, Stavridis M, Griffiths D, et al. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat Biotechnol 2003; 21 : 183–6.
  26. Gottlieb DI. Large-scale sources of neural stem cells. Annu Rev Neurosci 2002; 25 : 381–407.
  27. Okada Y, Shimazaki T, Sobue G, et al. Retinoic-acid-concentration-dependent acquisition of neural cell identity during in vitro differentiation of mouse embryonic stem cells. Dev Biol 2004; 275 : 124–42.
  28. Ruiz I, Altaba A, Stecca B, Sanchez P. Hedgehog-Gli signaling in brain tumors : stem cells and paradevelopmental programs in cancer. Cancer Lett 2004; 204 : 145–57.
  29. Lang KJ, Rathjen J, Vassilieva S, et al. Differentiation of embryonic stem cells to a neural fate : a route to re-building the nervous system ? J Neurosci Res 2004; 76 : 184–92.
  30. Mizuseki K, Sakamoto T, Watanabe K, et al. Generation of neural crest-derived peripheral neurons and floor plate cells from mouse and primate embryonic stem cells. Proc Natl Acad Sci USA 2003; 100 : 5828–33.
  31. Wichterle H, Lieberam I, Porter JA, et al. Directed differentiation of embryonic stem cells into motor neurons. Cell 2002; 110 : 385–97.
  32. Shiotsugu J, Katsuyama Y, Arima K, et al. Multiple points of interaction between retinoic acid and FGF signaling during embryonic axis formation. Development 2004; 131 : 2653–67.
  33. Altmann CR, Bell E, Sczyrba A, et al. Microarray-based analysis of early development in Xenopus laevis. Dev Biol 2001; 236 : 64–75.
  34. Maye P, Becker S, Kasameyer E, et al. Indian hedgehog signaling in extraembryonic endoderm and ectoderm differentiation in ES embryoid bodies. Mech Dev 2000; 94 : 117–32.
  35. Maye P, Becker S, Siemen H, et al. Hedgehog signaling is required for the differentiation of ES cells into neurectoderm. Dev Biol 2004; 265 : 276–90.
  36. Barberi T, Klivenyi P, Calingasan NY, et al. Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nat Biotechnol 2003; 21 : 1200–7.
  37. Simon HH, Bhatt L, Gherbassi D, et al. Midbrain dopaminergic neurons : determination of their developmental fate by transcription factors. Ann NY Acad Sci 2003; 991 : 36–47.
  38. Kim JH, Auerbach JM, Rodriguez-Gomez JA, et al. Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson’s disease. Nature 2002; 418 : 50–6.
  39. Jiang C, Wan X, He Y, et al. Age-dependent dopaminergic dysfunction in Nurr1 knockout mice. Exp Neurol 2005; 191 : 154–62.
  40. Chandran S, Kato H, Gerreli D, et al. FGF-dependent generation of oligodendrocytes by a hedgehog-independent pathway. Development 2003; 130 : 6599–609.
  41. Brustle O, Jones KN, Learish RD, et al. Embryonic stem cell-derived glial precursors : a source of myelinating transplants. Science 1999; 285 : 754–6.
  42. Liu S, Qu Y, Stewart TJ, et al. Embryonic stem cells differentiate into oligodendrocytes and myelinate in culture and after spinal cord transplantation. Proc Natl Acad Sci USA 2000; 97 : 6126–31.
  43. Xian HQ, McNichols E, St Clair A, et al. A subset of ES-cell-derived neural cells marked by gene targeting. Stem Cells 2003; 21 : 41–9.
  44. Angelov DN, Arnhold S, Andressen C, et al. Temporospatial relationships between macroglia and microglia during in vitro differentiation of murine stem cells. Dev Neurosci 1998; 20 : 42–51.
  45. Xian H, Gottlieb DI. Dividing Olig2-expressing progenitor cells derived from ES cells. Glia 2004; 47 : 88–101.
  46. Gardner RL, Brook FA. Reflections on the biology of embryonic stem (ES) cells. Int J Dev Biol 1997; 41 : 235–43
  47. Ahn JI, Lee KH, Shin DM, et al. Comprehensive transcriptome analysis of differentiation of embryonic stem cells into midbrain and hindbrain neurons. Dev Biol 2004; 265 : 491–501.
  48. Appel B, Eisen JS. Retinoids run rampant : multiple roles during spinal cord and motor neuron development. Neuron 2003; 40 : 461–4.
  49. Arnhold S, Lenartz D, Kruttwig K, et al. Differentiation of green fluorescent protein-labeled embryonic stem cell-derived neural precursor cells into Thy-1-positive neurons and glia after transplantation into adult rat striatum. J Neurosurg 2000; 93 : 1026–32.
  50. Strubing C, Ahnert-Hilger G, Shan J, et al. Differentiation of pluripotent embryonic stem cells into the neuronal lineage in vitro gives rise to mature inhibitory and excitatory neurons. Mech Dev 1995; 53 : 275–87.
  51. Cazillis M, Gonzalez BJ, Billardon C, et al. VIP and PACAP induce selective neuronal differentiation of mouse embryonic stem cells. Eur J Neurosci 2004; 19 : 798–808.
  52. Kawasaki H, Mizuseki K, Nishikawa S, et al. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron 2000; 28 : 31–40.

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