Instabilité des microsatellites : un nouveau mécanisme de carcinogenèse associé à l’immunodépression dans les lymphomes non hodgkiniens chez l’homme

Claire Borie; Martine Raphaël; Richard Hamelin; Alex Duval

doi:10.1051/medsci/2004206-7641

Accès gratuit

Numéro		Med Sci (Paris) Volume 20, Numéro 6-7, Juin-Juillet 2004


Page(s)		641 - 642
Section		Le Magazine : Nouvelles
DOI		https://doi.org/10.1051/medsci/2004206-7641
Publié en ligne		15 juin 2004

Aaltonen LA, Peltomäki P, Leach FS, et al. Clues to the pathogenesis of familial colorectal cancer. Science 1993; 260 : 812–6. [Google Scholar]
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Ionov Y, Peinado M, Malkhosyan S, et al. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993; 363 : 558–61. [Google Scholar]
Boland CR, Thibodeau SN, Hamilton SR, et al. A National cancer institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998; 58 : 5248–57. [Google Scholar]
Suraweera N, Duval A, Reperant M, et al. Evaluation of tumor microsatellite instability using five quasimonomorphic monoculceotide repeats and pentaplex PCR. Gastroenterology 2002; 123 : 1804–11. [Google Scholar]
Duval A, Raphael M, Brennetot C, et al. The mutator pathway is a feature of immunodeficiency-related lymphomas. Proc Natl Acad Sci USA 2004; 101 : 5002–7. [Google Scholar]
Carbone A. Emerging pathways in the development of AIDS-related lymphomas. Lancet Oncol 2003; 4 : 22–9. [Google Scholar]
Leblond V, Dedhin N, Mamzer Bruneel MF, et al. Identification of prognostic factors in 61 patients with posttransplantation lymphoproliferative disorders. J Clin Oncol 2001; 19 : 772–8. [Google Scholar]
Duval A, Rolland S, Compoint A, et al. Evolution of instability at coding and non-coding repeat sequences in human MSI-H colorectal cancers. Hum Mol Genet 2001; 10 : 513–8. [Google Scholar]
Duval A, Hamelin R. Mutations at coding repeat sequences in mismatch repair deficient human cancers: Toward a new concept of target genes for instability. Cancer Res 2002; 62 : 2447–54. [Google Scholar]
Lothe RA, Peltomaki P, Meling GI, et al. Genomic instability in colorectal cancer: Relationship to clinicopathological variables and family history. Cancer Res 1993; 53 : 5849–52 [Google Scholar]

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[1] Aaltonen LA, Peltomäki P, Leach FS, et al. Clues to the pathogenesis of familial colorectal cancer. Science 1993; 260 : 812–6. [Google Scholar]

[2] Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993; 260 : 816–9. [Google Scholar]

[3] Ionov Y, Peinado M, Malkhosyan S, et al. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993; 363 : 558–61. [Google Scholar]

[4] Boland CR, Thibodeau SN, Hamilton SR, et al. A National cancer institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998; 58 : 5248–57. [Google Scholar]

[5] Suraweera N, Duval A, Reperant M, et al. Evaluation of tumor microsatellite instability using five quasimonomorphic monoculceotide repeats and pentaplex PCR. Gastroenterology 2002; 123 : 1804–11. [Google Scholar]

[6] Duval A, Raphael M, Brennetot C, et al. The mutator pathway is a feature of immunodeficiency-related lymphomas. Proc Natl Acad Sci USA 2004; 101 : 5002–7. [Google Scholar]

[7] Carbone A. Emerging pathways in the development of AIDS-related lymphomas. Lancet Oncol 2003; 4 : 22–9. [Google Scholar]

[8] Leblond V, Dedhin N, Mamzer Bruneel MF, et al. Identification of prognostic factors in 61 patients with posttransplantation lymphoproliferative disorders. J Clin Oncol 2001; 19 : 772–8. [Google Scholar]

[9] Duval A, Rolland S, Compoint A, et al. Evolution of instability at coding and non-coding repeat sequences in human MSI-H colorectal cancers. Hum Mol Genet 2001; 10 : 513–8. [Google Scholar]

[10] Duval A, Hamelin R. Mutations at coding repeat sequences in mismatch repair deficient human cancers: Toward a new concept of target genes for instability. Cancer Res 2002; 62 : 2447–54. [Google Scholar]

[11] Lothe RA, Peltomaki P, Meling GI, et al. Genomic instability in colorectal cancer: Relationship to clinicopathological variables and family history. Cancer Res 1993; 53 : 5849–52 [Google Scholar]