Accès gratuit
Numéro
Med Sci (Paris)
Volume 20, Numéro 1, Janvier 2004
Page(s) 68 - 72
Section M/S revues
DOI https://doi.org/10.1051/medsci/200420168
Publié en ligne 15 janvier 2004
  1. Nelson N. Metal ion transporters and homeostasis. EMBO J 1999; 18 : 4361–71.
  2. Ponka P, Beaumont C, Richardson DR. Function and regulation of transferrin and ferritin. Semin Hematol 1998; 35 : 35–54.
  3. Trinder D, Baker E. Transferin receptor 2 : a new molecule in iron metabolism. Int J Biochem Cell Biol 2003; 35 : 292–6.
  4. Verroust PJ, Kozyraki R. Cubiline : rôle physiopathologique et relations avec la mégaline. Med Sci (Paris) 2003; 19 : 337–43.
  5. McKie AT, Barrow D, Latunde-Dada GO, et al. An iron-regulated ferric reductase associated with the absorption of dietary iron. Science 2001; 291 : 1755–9.
  6. Gunshin H, Mackenzie B, Berger UV, et al. Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 1997; 388 : 482–8.
  7. Canonne-Hergaux F, Gruenheid S, Ponka P, Gros P. Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron. Blood 1999; 93 : 4406–17.
  8. Fleming MD, Trenor CC III, Su MA, et al. Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene. Nat Genet 1997; 16 : 383–6.
  9. McKie AT, Marciani P, Rolfs A, et al. A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Mol Cell 2000; 5 : 299–309.
  10. Abboud S, Haile DJ. A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J Biol Chem 2000; 275 : 19906–12.
  11. Donovan A, Brownlie A, Zhou Y, et al. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature 2000; 403 : 776–81.
  12. Vulpe CD, Kuo YM, Murphy TL, et al. Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse. Nat Genet 1999; 21 : 195–9.
  13. Knutson M, Wessling-Resnick M. Iron metabolism in the reticuloendothelial system. Crit Rev Biochem Biol 2003; 38 : 61–88.
  14. Montosi G, Donovan A, Totaro A, et al. Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. J Clin Invest 2001; 108 : 619–23.
  15. Devalia V, Carter K, Walker AP, et al. Autosomal dominant reticuloendothelial iron overload associated with a 3-base pair deletion in the ferroportin 1 gene (SLC11A3). Blood 2002; 100 : 695–7.
  16. Harris ZL, Durley AP, Man TK, Gitlin JD. Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux. Proc Natl Acad Sci USA 1999; 96 : 10812–7.
  17. Harris ZL, Klomp LWJ, Gitlin JD. Aceruloplasminemia : an inherited neurodegenerative disease with impairment of iron homeostasis. Am J Clin Nutr 1998; 67 : 972S.
  18. Andrews NC. Disorders of iron metabolism. N Engl J Med 1999; 341 : 1986–95.
  19. Feder JN, Gnirke A, Thomas W, et al. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet 1996; 13 : 399–408.
  20. Ramalingam TS, West AP Jr, Lebron JA, et al. Binding to the transferrin receptor is required for endocytosis of HFE and regulation of iron homeostasis. Nat Cell Biol 2000; 2 : 953–7.
  21. Hunter HN, Fulton DB, Ganz T, Vogel HJ. The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis. J Biol Chem 2002; 277 : 37597–603.
  22. Pigeon C, Ilyin G, Courselaud B, et al. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 2001; 276 : 7811–9.
  23. Nicolas G, Bennoun M, Devaux I, et al. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci USA 2001; 98 : 8780–5.
  24. Roetto A, Papanikolaou G, Politou M, et al Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis. Nat Genet 2003; 33 : 21–2.
  25. Nicolas G, Bennoun M, Porteu A, et al Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc Natl Acad Sci USA 2002; 99 : 4596–601.
  26. Nicolas G, Viatte L, Lou DQ, et al. Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis. Nat Genet 2003; 34 : 97–101.
  27. Bridle KR, Frazer DM, Wilkins SJ, et al. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet 2003; 361 : 669–73.
  28. Nemeth E, Valore EV, Territo M, Schiller G, Lichtenstein A, Ganz T. Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood 2003; 101 : 2461–3.
  29. Nicolas G, Chauvet C, Viatte L, et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest 2002; 110 : 1037–44.

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