Rôles physiologiques de l’AMP-activated protein kinase (AMPK)

Fabrizio Andreelli; Benoît Viollet; Sophie Vaulont

doi:10.1051/medsci/2003195541

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Volume 19 / Numéro 5 (Mai 2003)

Med Sci (Paris), 19 5 (2003) 541-542

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Numéro		Med Sci (Paris) Volume 19, Numéro 5, Mai 2003


Page(s)		541 - 542
Section		Le Magazine : Nouvelles
DOI		https://doi.org/10.1051/medsci/2003195541
Publié en ligne		15 mai 2003

Hardie DG, Carling D, Carlson M. The AMPactivated/ SNF1protein kinase subfamily: metabolic sensors of the eukaryotic cell ? Annu Rev Biochem 1998; 67: 821–55. [Google Scholar]
Winder WW, Hardie DG. AMPactivated protein kinase, a metabolic master switch: possible roles in type 2 diabetes. Am J Physiol 1999; 277: E1–10. [Google Scholar]
Bergeron R, Previs SF, Cline GW, et al. Effect of 5- aminoimidazole-4- carboxamide-1-beta-Dribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats. Diabetes 2001; 50: 1076–82 [Google Scholar]
Bergeron R, Russell RR, Young LH, et al. Effect of AMPK activation on muscle glucose metabolism in conscious rats. Am J Physiol 1999; 276: E938–44. [Google Scholar]
Minokoshi Y, Kim YB, Peroni OD, et al. Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature 2002; 415: 339–43. [Google Scholar]
Zhou G, Myers R, Li Y, et al.Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 2001; 108: 1167–74. [Google Scholar]
Viollet B, Andreelli F, Jorgensen SB, et al. The AMP-activated protein kinase α2 catalytic subunit controls whole body insulin sensitivity. J Clin Invest 2003; 111: 91–8. [Google Scholar]

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[1] Hardie DG, Carling D, Carlson M. The AMPactivated/ SNF1protein kinase subfamily: metabolic sensors of the eukaryotic cell ? Annu Rev Biochem 1998; 67: 821–55. [Google Scholar]

[2] Winder WW, Hardie DG. AMPactivated protein kinase, a metabolic master switch: possible roles in type 2 diabetes. Am J Physiol 1999; 277: E1–10. [Google Scholar]

[3] Bergeron R, Previs SF, Cline GW, et al. Effect of 5- aminoimidazole-4- carboxamide-1-beta-Dribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats. Diabetes 2001; 50: 1076–82 [Google Scholar]

[4] Bergeron R, Russell RR, Young LH, et al. Effect of AMPK activation on muscle glucose metabolism in conscious rats. Am J Physiol 1999; 276: E938–44. [Google Scholar]

[5] Minokoshi Y, Kim YB, Peroni OD, et al. Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature 2002; 415: 339–43. [Google Scholar]

[6] Zhou G, Myers R, Li Y, et al.Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 2001; 108: 1167–74. [Google Scholar]

[7] Viollet B, Andreelli F, Jorgensen SB, et al. The AMP-activated protein kinase α2 catalytic subunit controls whole body insulin sensitivity. J Clin Invest 2003; 111: 91–8. [Google Scholar]