Free Access
Issue
Med Sci (Paris)
Volume 18, Number 1, Janvier 2002
Page(s) 45 - 54
Section M/S Revues : Articles de Synthèse
DOI https://doi.org/10.1051/medsci/200218145
Published online 15 January 2002
  1. Holbrook KA, Wolff K. The structure and development of skin. In: Fitzpatrick TB, et al., eds. Dermatology in general medicine. New York: McGraw-Hill, 1993 : 97–144. [Google Scholar]
  2. Fuchs E, Byrne C. The epidermis: rising to the surface. Curr Opin Genet Dev 1994; 4 : 725–36. [Google Scholar]
  3. Steinert PM. The complexity and redundancy of epithelial barrier function. J Cell Biol 2000; 151 : F5–7. [Google Scholar]
  4. Fuchs E. Keratins and the skin. Annu Rev Cell Dev Biol 1995; 11 : 123–53. [Google Scholar]
  5. Fuchs E, Weber K. Intermediate filaments: structure, dynamics, function, and disease. Annu Rev Biochem 1994; 63 : 345–82. [Google Scholar]
  6. Herrmann H, Aebi U. Intermediate filaments and their associates: multi-talented structural elements specifying cytoarchitecture and cytodynamics. Curr Opin Cell Biol 2000; 12 : 79–90. [Google Scholar]
  7. Coulombe PA, Bousquet O, Ma L, et al. The ’ins’ and ’outs’ of intermediate filament organization. Trends Cell Biol 2000; 10 : 420–8. [Google Scholar]
  8. Moll R, Franke WW, Schiller DL, et al. The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 1982; 31 : 11–24. [Google Scholar]
  9. Powell BC, Rogers GE. The role of keratin proteins and their genes in the growth, structure and properties of hair. EXS 1997; 78 : 59–148. [Google Scholar]
  10. Coulombe PA. The cellular and molecular biology of keratins: beginning a new era. Curr Opin Cell Biol 1993; 5 : 17–29. [Google Scholar]
  11. O’Guin WM, Schermer A, Lynch M, et al. Differenciation-specific expression of keratin pairs. In: Goldman RD, Steinert PM, eds. Cellular and molecular biology of intermediate filaments. New York: Plenum Publishing Company, 1990 : 301–34. [Google Scholar]
  12. Paladini RD, Coulombe PA. The functional diversity of epidermal keratins revealed by the partial rescue of the keratin 14 null phenotype by keratin 16. J Cell Biol 1999; 146 : 1185–201. [Google Scholar]
  13. Fuchs E, Cleveland DW. A structural scaffolding of intermediate filaments in health and disease. Science 1998; 279 : 514–9. [Google Scholar]
  14. Irvine AD, McLean WH. Human keratin diseases: the increasing spectrum of disease and subtlety of the phenotype-genotype correlation. Br j Dermatol 1999; 140 : 815–28. [Google Scholar]
  15. Coulombe PA, Fuchs E, Molecular mechanisms of keratin gene disorders and other bullous diseases of the skin. In: Citi S, ed. Molecular mechanisms of epithelial cell junctions: from development to disease. Austin, TX: R.G. Landes Company, 1994 : 259–85. [Google Scholar]
  16. Ma L, Yamada S, Wirtz D, et al. A ’hot-spot’ mutation alters the mechanical properties of keratin filament networks. Nat Cell Biol 2001; 3 : 503–6. [Google Scholar]
  17. Takahashi K, Paladini RD, Coulombe PA. Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms.J Biol Chem 1995; 270 : 18581–92. [Google Scholar]
  18. Blessing M, Zentgraf H, Jorcano JL. Differentially expressed bovine cytokeratin genes. Analysis of gene linkage and evolutionary conservation of 5’-ups-tream sequences. EMBO J 1987; 6 : 567–75. [Google Scholar]
  19. Takahashi K, Yan B, Yamanishi K, et al. The two functional keratin 6 genes of mouse are differentially regulated and evolved independently from their human orthologs. Genomics 1998; 53 : 170–83. [Google Scholar]
  20. McGowan K, Coulombe PA. The wound repair-associated keratins 6, 16, and 17. Insights into the role of intermediate filaments in specifying keratinocyte cytoarchitecture. Subcell Biochem 1998; 31 : 173–204. [Google Scholar]
  21. Porter RM, Hutcheson AM, Rugg EL, et al. cDNA cloning, expression, and assembly characteristics of mouse keratin 16. J Biol Chem 1998; 273 : 32265–72. [Google Scholar]
  22. McGowan KM, Coulombe PA. Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development. J Cell Biol 1998; 143 : 469–86. [Google Scholar]
  23. Yoshikawa K, Katagata Y, Kondo S. Relative amounts of keratin 17 are higher than those of keratin 16 in hairfollicle-derived tumors in comparison with nonfollicular epithelial skin tumors. J Invest Dermatol 1995; 104 : 396–400. [Google Scholar]
  24. McGowan KM, Coulombe PA. Keratin 17 expression in the hard epithelial context of the hair and nail, and its relevance for the pachyonychia congenita phenotype.J Invest Dermatol 2000; 114 : 1101–7. [Google Scholar]
  25. Moll R, Krepler R, Franke WW. Complex cytokeratin polypeptide patterns observed in certain human carcinomas. Differentiation 1983; 23 : 256–69. [Google Scholar]
  26. Weiss RA, Eichner R, Sun TT. Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48-and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes.J Cell Biol 1984; 98 : 1397–406. [Google Scholar]
  27. Stoler A, Duvic M, Fuchs E. Unusual patterns of keratin expression in the overlying epidermis of patients with dermatofibromas: biochemical alterations in the epidermis as a consequence of dermal tumors. J Invest Dermatol 1989; 93 : 728–38. [Google Scholar]
  28. Mansbridge JN, Knapp AM. Changes in keratinocyte maturation during wound healing. J Invest Dermatol 1987; 89 : 253–63. [Google Scholar]
  29. Paladini RD, Takahashi K, Bravo NS, et al. Onset of reepithelialization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes: defining a potential role for keratin 16. J Cell Biol 1996; 132 : 381–97. [Google Scholar]
  30. Ramirez A, Vidal M, Bravo A, et al. A 5’-upstream region of a bovine keratin 6 gène confers tissue-specific expression and hyperproliferation-related induction in transgenic mice. Proc Natl Acad Sci USA 1995; 92 : 4783–7. [Google Scholar]
  31. Feinstein A, Friedman J, Schewach-Millet M. Pachyonychia congenita. J Am Acad Dermatol 1988; 19 : 705–11. [Google Scholar]
  32. McLean WH, Rugg EL, Lunny DP, et al. Keratin 16 and keratin 17 mutations cause pachyonychia congenita. Nat Genet 1995; 9 : 273–8. [Google Scholar]
  33. Coulombe PA. Towards a molecular definition of keratinocyte activation after acute injury to stratified epithelia. Biochem Biophys Res Commun 1997; 236 : 231–8. [Google Scholar]
  34. Takahashi K, Folmer J, Coulombe PA. Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skin. J Cell Biol 1994; 127 : 505–20. [Google Scholar]
  35. Paladini RD, Coulombe PA. Directed expression of keratin 16 to the progenitor basal cells of transgenic mouse skin delays skin maturation. J Cell Biol 1998; 142 : 1035–51. [Google Scholar]
  36. Bousquet O, Ma L, Yamada S, Gu C, Idei T, Takahashi K, Wirtz D, Coulombe PA. The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitro. J Cell Biol 2001; 155 : 747–53 [Google Scholar]
  37. Wawersik M, Coulombe PA. Forced expression of keratin 16 alters the adhesion, differentiation, and migration of mouse skin keratinocytes. Moi Biol Cell 2000; 11 : 3315–27. [Google Scholar]
  38. Wojcik SM, Bundman DS, Roop DR. Delayed wound healing in keratin 6a knockout mice. Mol Cell Biol 2000; 20 : 5248–55. [Google Scholar]
  39. Clark RAF. Mechanisms of cutaneous wound repair. In: Fitzpatrick TB, et al. eds. Dermatology in general medicine, vol. 1. New York: McGraw-Hill, 1993: 473–88. [Google Scholar]
  40. Schermer A, Jester JV, Hardy C, et al. Transient synthesis of K6 and K16 keratins in regenerating rabbit corneal epithelium: keratin markers for an alternative pathway of keratinocyte differentiation. Differentiation 1989; 42 : 103–10. [Google Scholar]
  41. Byrne C, Tainsky M, Fuchs E. Programming gene expression in developing epidermis. Development 1994; 120 : 2369–83. [Google Scholar]
  42. Sanes JR, Rubenstein JL, Nicolas JF. Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos. EMBO J 1986; 5 : 3133–42. [Google Scholar]
  43. Bousquet O, Coulombe PA. Cytoskeleton: missing links found? Curr Biol 1996; 6 : 1563–6. [Google Scholar]
  44. Murillas R, Larcher F, Conti CJ, et al. Expression of a dominant negative mutant of epidermal growthfactor receptor in the epidermis of transgenic mice elicits striking alterations in hair fol-licle development and skin structure. EMBO J 1995; 14 : 5216–23. [Google Scholar]
  45. Stoscheck CM, Nanney LB, King LEJ. Quantitative determination of EGF-R during epidermal wound healing. J Invest Dermatol 1992; 99 : 645–9. [Google Scholar]
  46. Paramio JM, Casanova ML, Segrelles C, et al. Modulation of cell proliferation by cytokeratins K10 and K16. Mol Cell Biol 1999; 19 : 3086–94. [Google Scholar]
  47. Liao J, Omary MB. 14-3-3 proteins associate with phosphorylated simple epithelial keratins during cell cycle progression and act as a solubility cofactor. J Cell Biol 1996; 133 : 345–57. [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.