Free Access
Tableau I.
Structures des RCPG liant des ligands diffusibles. PDB : protein data bank.
| Récepteur | Ligand | Stratégie utilisée | Code identifiant dans la PDB | Réf. |
|---|---|---|---|---|
| ZM241385 | Lysozyme T4 remplace la boucle intracellulaire 3 | 3EML | [15] | |
| UK-432097 | 3QAK | [38] | ||
| ZM241385 | 3PWH | |||
| Adénosine humain (A2AR) | XAC | 3REY | [27] | |
| Caféine | Mutations thermostabilisantes | 3RFM | ||
| Adénosine | 2YDO | |||
| NECA | 2YDV | [36] | ||
| Cyanopindolol | 2VT4, 2YCX, 2YCY, 2YCZ | [26, 28] | ||
| Carazolol | 2YCW | [28] | ||
| β1-adrénergique de la dinde (β1-AR) | Dobutamine | Mutations thermostabilisantes | 2Y00, 2Y01 | |
| Carmotorol | 2Y02 | [31] | ||
| Isoprénaline | 2Y03 | |||
| Salbutamol | 2Y04 | |||
| Carazolol | Anticorps Fab5 | 2R4S 2R4R | [9] | |
| Carazolol | 2RH1 | [12, 13] | ||
| Timolol | 3D4S | [11] | ||
| ICI118551 | Lysozyme T4 remplace la boucle intracellulaire 3 | 3NY8 | ||
| β2-adrénergique humain (β2-AR) | Agoniste inverse | 3NY9 | [14] | |
| Alprénolol | 3NYA | |||
| FAUC50 | 3PDS | [32] | ||
| BI-167107 | Lysozyme T4 remplace la boucle intracellulaire 3 ; anticorps de lama nb80 | 3P0G | [29] | |
| Lysozyme T4 fusionné à l’extrémité amino-terminale ; protéine Gs (α, β et γ) | 3SN6 | [39] | ||
| Chémokine humain (CXCR4) | IT1t | Lysozyme T4 remplace la boucle intracellulaire 3 | 3ODU, 3OE6, 3OE8, 3OE9 | [18] |
| Peptide CVX15 | 3OE0 | [18] | ||
| Dopamine 3 humain (D3R) | Éticlopride | Lysozyme T4 remplace la boucle intracellulaire 3 | 3PBL | [16] |
| Histamine H1 humain (H1R) | Doxepin | Lysozyme T4 remplace la boucle intracellulaire 3 | 3RZE | [17] |
| Muscarinique (M2) | QNB | Lysozyme T4 remplace la boucle intracellulaire 3 | 3UON | [20] |
| Muscarinique (M3) | Tiotropium | Lysozyme T4 remplace la boucle intracellulaire 3 | 4DAJ | [19] |
| Spingosine-1-phosphate (S1P1) | ML056 | Lysozyme T4 remplace la boucle intracellulaire 3 | 3V2W 3V2Y | [21] |
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.