EDP Sciences logo
Subscriber Authentication Point
Search
Menu
Home All issues Volume 42 / No 2 (Février 2026) Med Sci (Paris), 42 2 (2026) 121-124 References
Open Access
Issue
Med Sci (Paris)
Volume 42, Number 2, Février 2026
Page(s) 121 - 124
Section Nouvelles
DOI https://doi.org/10.1051/medsci/2026004
Published online 24 February 2026
  1. Morton CC, Nance WE. Newborn hearing screening: a silent revolution. N Engl J Med 2006 ; 354 : 2151–64. [Google Scholar]
  2. Yasunaga S, Grati M, Chardenoux S, et al. OTOF encodes multiple long and short isoforms: Genetic evidence that the long ones underlie recessive deafness DFNB9. Am J Hum Genet 2000 ; 67 : 591–600. [Google Scholar]
  3. Roux I, Safieddine S, Nouvian R, et al. Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse. Cell 2006 ; 127 : 277–89. [CrossRef] [PubMed] [Google Scholar]
  4. Hardelin J-P, Safieddine S. Vers une thérapie génique de certaines surdités congénitales ? Med Sci (Paris) 2019 ; 35 : 1213–15. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  5. Akil O, Dyka F, Calvet C, et al. Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model. Proc Natl Acad Sci USA 2019 ; 116 : 4496–501. [Google Scholar]
  6. Al-Moyed H, Cepeda AP, Jung S, et al. A dual-AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock-out mice. EMBO Mol Med 2019 ; 11 : e9396. [Google Scholar]
  7. Lv J, Wang H, Cheng X, et al. AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial. Lancet 2024 ; 403 : 2317–25. [Google Scholar]
  8. Wang H, Chen Y, Lv J, et al. Bilateral gene therapy in children with autosomal recessive deafness 9: single-arm trial results. Nat Med 2024 ; 30 : 1898–904. [Google Scholar]
  9. Zhang L, Dong D, Yin Y, et al. Audiological characteristics following gene therapy in patients with autosomal recessive deafness 9. Med 2025 ; 6 : 100696. [Google Scholar]
  10. Zhang J, Guo Z, Pan C, et al. Preliminary evidence for enhanced auditory cortex activation and mental development after gene therapy in children with autosomal recessive deafness 9. Nat Hum Behav 2025 ; 9 : 1457–69. [Google Scholar]
  11. Landegger LD, Pan B, Askew C, et al. A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear. Nat Biotechnol 2017 ; 35 : 280–4. [Google Scholar]
  12. Qi J, Tan F, Zhang L, et al. AAV-mediated gene therapy restores hearing in patients with DFNB9 deafness. Adv Sci 2024 ; 11 : 2306788. [Google Scholar]
  13. Qi J, Zhang L, Lu L, et al. AAV gene therapy for autosomal recessive deafness 9: a single-arm trial. Nat Med 2025 ; 31 : 2917–26. [Google Scholar]
  14. Sharma A, Gilley PM, Dorman MF, et al. Deprivation-induced cortical reorganization in children with cochlear implants. Int J Audiol 2007 ; 46 : 494–9. [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.