Open Access
Issue
Med Sci (Paris)
Volume 42, Number 1, Janvier 2026
Page(s) 33 - 36
Section Nouvelles
DOI https://doi.org/10.1051/medsci/2025248
Published online 23 January 2026
  1. Sun L, Wu J, Du F, et al. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 2013 ; 339 : 786-91. [CrossRef] [PubMed] [Google Scholar]
  2. Dvorkin S, Cambier S, Volkman HE, et al. New frontiers in the cGAS-STING intracellular DNA-sensing pathway. Immunity 2024 ; 57 : 718-30. [Google Scholar]
  3. Lahaye X, Gentili M, Silvin A, et al. NONO detects the nuclear HIV capsid to promote cGAS-mediated innate immune activation. Cell 2018 ; 175 : 488-501.e22. [Google Scholar]
  4. Morchikh M, Cribier A, Raffel R, et al. HEXIM1 and NEAT1 long non-coding RNA form a multi-subunit complex that regulates DNA-mediated innate immune response. Mol Cell 2017 ; 67 : 387-99.e5. [Google Scholar]
  5. Silvin A, Manel N. Innate immune sensing of HIV infection. Curr Opin Immunol 2015 ; 32 : 54-60. [Google Scholar]
  6. Sumner RP, Harrison L, Touizer E, et al. Disrupting HIV-1 capsid formation causes cGAS sensing of viral DNA. EMBO J 2020 ; 39 : e103958. [Google Scholar]
  7. Geis FK, Goff SP. Unintegrated HIV-1 DNAs are loaded with core and linker histones and transcriptionally silenced. Proc Natl Acad Sci USA 2019 ; 116 : 23735-42. [Google Scholar]
  8. Machida S, Depierre D, Chen H-C, et al. Exploring histone loading on HIV DNA reveals a dynamic nucleosome positioning between unintegrated and integrated viral genome. Proc Natl Acad Sci. USA 2020 ; 117 : 6822-30. [Google Scholar]
  9. Thenin-Houssier S, Machida S, Jahan C, et al. POLE3 is a repressor of unintegrated HIV-1 DNA required for efficient virus integration and escape from innate immune sensing. Sci Adv 2023 ; 9 : eadh3642. [Google Scholar]
  10. Jahan C, Bonnet-Madin L, Machida S, et al. Unintegrated HIV-1 DNA recruits cGAS via its histone-binding domain to escape innate immunity. Proc Natl Acad Sci USA 2025 ; 122 : e2424465122. [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.