Open Access
Med Sci (Paris)
Volume 36, Number 5, Mai 2020
Page(s) 458 - 460
Section Le Magazine
Published online 26 May 2020
  1. World Health Organization. Global report on diabetes 2016. Geneva : WHO, 2016: 88 p. [Google Scholar]
  2. PanneerselvamA, KannanA, Mariajoseph-AntonyLF, et al. PAX proteins and their role in pancreas. Diabetes Res Clin Pract 2019 ; 155 : 107792. [CrossRef] [PubMed] [Google Scholar]
  3. BrunT, FranklinI, St-OngeL, et al. The diabetes-linked transcription factor PAX4 promotes β-cell proliferation and survival in rat and human islets. J Cell Biol 2004 ; 167 : 1123–1135. [CrossRef] [PubMed] [Google Scholar]
  4. HeKHH, LorenzoPI, BrunT, et al. In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice. Diabetes 2011 ; 60 : 1705–1715. [CrossRef] [PubMed] [Google Scholar]
  5. Mellado-GilJM, Jiménez-MorenoCM, Martin-MontalvoA, et al. PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus. Diabetologia 2016 ; 59 : 755–765. [CrossRef] [PubMed] [Google Scholar]
  6. ChouFC, ShiehSJ, SytwuHK. Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice. Eur J Immunol 2009 ; 39 : 2403–2411. [CrossRef] [PubMed] [Google Scholar]
  7. CollombatP, XuX, RavassardP, et al. The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into α- and subsequently β-cells. Cell 2009 ; 138 : 449–462. [CrossRef] [PubMed] [Google Scholar]
  8. CourtneyM, GjernesE, DruelleN, et al. The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells. PLoS Genet 2013 ; 9 : e1003934. [CrossRef] [PubMed] [Google Scholar]
  9. Ben-OthmanN, VieiraA, CourtneyM, et al. Long-term GABA administration induces α cell-mediated β-like cell neogenesis. Cell 2017 ; 168 : 73–85. [CrossRef] [PubMed] [Google Scholar]
  10. ZhangY, FavaGE, WangH, et al. PAX4 gene transfer induces α-to-β cell phenotypic conversion and confers therapeutic benefits for diabetes treatment. Mol Ther 2016 ; 24 : 251–260. [CrossRef] [PubMed] [Google Scholar]

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