Open Access
Issue
Med Sci (Paris)
Volume 36, Number 5, Mai 2020
Page(s) 465 - 471
Section M/S Revues
DOI https://doi.org/10.1051/medsci/2020078
Published online 26 May 2020
  1. Bourgeois D, Bouchard P, Mattout C. Epidemiology of periodontal status in dentate adults in France, 2002–2003. J Periodont Res 2007 ; 42 : 21–27. [Google Scholar]
  2. Kumar PS. From focal sepsis to periodontal medicine: a century of exploring the role of the oral microbiome in systemic disease. J Physiol (Lond) 2017 ; 595 : 465–476. [CrossRef] [Google Scholar]
  3. Sebbag M, Chapuy-Regaud S, Auger I, et al. Clinical and pathophysiological significance of the autoimmune response to citrullinated proteins in rheumatoid arthritis. Joint Bone Spine 2004 ; 71 : 493–502. [CrossRef] [PubMed] [Google Scholar]
  4. McGraw WT, Potempa J, Farley D, et al. Purification, characterization, and sequence analysis of a potential virulence factor from Porphyromonas gingivalis, peptidylarginine deiminase. Infect Immun 1999 ; 67 : 3248–3256. [CrossRef] [PubMed] [Google Scholar]
  5. Vossenaar ER, Zendman AJW, van Venrooij WJ, et al. PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease. Bioessays 2003 ; 25 : 1106–1118. [CrossRef] [PubMed] [Google Scholar]
  6. Baka Z, György B, Géher P, et al. Citrullination under physiological and pathological conditions. Joint Bone Spine 2012 ; 79 : 431–436. [CrossRef] [PubMed] [Google Scholar]
  7. Branzk N, Lubojemska A, Hardison SE, et al. Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens. Nat Immunol 2014 ; 15 : 1017–1025. [CrossRef] [PubMed] [Google Scholar]
  8. Li P, Li M, Lindberg MR, et al. PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps. J Exp Med 2010 ; 207 : 1853–1862. [CrossRef] [PubMed] [Google Scholar]
  9. Gabarrini G, Chlebowicz MA, Vega Quiroz ME, et al. Conserved citrullinating exoenzymes in porphyromonas species. J Dent Res 2018 ; 97 : 556–562. [CrossRef] [PubMed] [Google Scholar]
  10. Gómez-Bañuelos E, Mukherjee A, Darrah E, et al. Rheumatoid arthritis-associated mechanisms of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. J Clin Med 2019 ; 8 : 1309. [Google Scholar]
  11. Potempa J Mydel P, Koziel J. The case for periodontitis in the pathogenesis of rheumatoid arthritis. Nat Rev Rheumatol 2017 ; 13 : 606–620. [CrossRef] [PubMed] [Google Scholar]
  12. Ancuta C, Iordache C, Ancuta E, et al. Rheumatoid arthritis and periodontal disease: a complex interplay, new developments in the pathogenesis of rheumatoid arthritis. Lazaros I. Sakkas, IntechOpen. doi: 10.5772/65863. https://www.intechopen.com/books/new-developments-in-the-pathogenesis-of-rheumatoid-arthritis/rheumatoid-arthritis-and-periodontal-disease-a-complex-interplay. [Google Scholar]
  13. Casiano-Colón A, Marquis RE. Role of the arginine deiminase system in protecting oral bacteria and an enzymatic basis for acid tolerance. Appl Environ Microbiol 1988 ; 54 : 1318–1324. [Google Scholar]
  14. Rodríguez SB, Stitt BL, Ash DE. Expression of peptidylarginine deiminase from Porphyromonas gingivalis in Escherichia coli: enzyme purification and characterization. Arch Biochem Biophys 2009 ; 488 : 14–22. [CrossRef] [PubMed] [Google Scholar]
  15. Aliko A Kamin´ska M, Bergum B, et al. Impact of Porphyromonas gingivalis peptidylarginine deiminase on bacterial biofilm formation, epithelial cell invasion, and epithelial cell transcriptional landscape. Sci Rep 2018 ; 8 : 14144. [CrossRef] [PubMed] [Google Scholar]
  16. How KY, Song KP, Chan KG. Porphyromonas gingivalis: an overview of periodontopathic pathogen below the gum line. Front Microbiol 2016; 7. [PubMed] [Google Scholar]
  17. Sato K, Yukitake H, Narita Y, et al. Identification of Porphyromonas gingivalis proteins secreted by the Por secretion system. FEMS Microbiol Lett 2013 ; 338 : 68–76. [PubMed] [Google Scholar]
  18. Bielecka E, Scavenius C, Kantyka T, et al. Peptidyl arginine deiminase from Porphyromonas gingivalis abolishes anaphylatoxin C5a activity. J Biol Chem 2014 ; 289 : 32481–32487. [CrossRef] [PubMed] [Google Scholar]
  19. Wegner N, Wait R, Sroka A, et al. Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: Implications for autoimmunity in rheumatoid arthritis. Arthritis Rheum 2010 ; 62 : 2662–2672. [CrossRef] [PubMed] [Google Scholar]
  20. Stobernack T, du Espina MT, Mulder LM, et al. A Secreted bacterial peptidylarginine deiminase can neutralize human innate immune defenses. mBio 2018; 9 : e01704–18. [PubMed] [Google Scholar]
  21. Stobernack T, Glasner C, Junker S, et al. Extracellular proteome and citrullinome of the oral pathogen Porphyromonas gingivalis. J Proteome Res 2016 ; 15 : 4532–4543. [PubMed] [Google Scholar]
  22. Khandpur R, Carmona-Rivera C, Vivekanandan-Giri A, et al. NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis. Sci Transl Med 2013; 5 : 178ra40–178ra40. [CrossRef] [PubMed] [Google Scholar]
  23. Wang F, Chen FF, Gao WB, et al. Identification of citrullinated peptides in the synovial fluid of patients with rheumatoid arthritis using LC-MALDI-TOF/TOF. Clin Rheumatol 2016 ; 35 : 2185–2194. [Google Scholar]
  24. Darrah E, Giles JT, Ols ML, et al. Erosive rheumatoid arthritis is associated with antibodies that activate PAD4 by increasing calcium sensitivity. Sci Transl Med 2013; 5 : 186ra65. [CrossRef] [PubMed] [Google Scholar]
  25. Roudier J, Balandraud N, Auger I. Anti PAD autoimmunity and rheumatoid arthritis. Joint Bone Spine 2018 ; 85 : 659–661. [CrossRef] [PubMed] [Google Scholar]
  26. Chen J, Wright K, Davis JM, et al. An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis. Genome Med 2016 ; 8 : 43. [CrossRef] [PubMed] [Google Scholar]
  27. de Oliveira Ferreira R, de Brito Silva R, Magno MB, et al. Does periodontitis represent a risk factor for rheumatoid arthritis? A systematic review and meta-analysis. Ther Adv Musculoskelet Dis 2019; 11 : 1759720X19858514. [Google Scholar]
  28. Chen HH, Huang N, Chen YM, et al. Association between a history of periodontitis and the risk of rheumatoid arthritis: a nationwide, population-based, case-control study. Ann Rheum Dis 2013 ; 72 : 1206–1211. [CrossRef] [PubMed] [Google Scholar]
  29. Bae SC, Lee YH. Association between anti-Porphyromonas gingivalis antibody, anti-citrullinated protein antibodies, and rheumatoid arthritis. Z Rheumatol 2018 ; 77 : 522–532. [CrossRef] [PubMed] [Google Scholar]
  30. Bender P, Bürgin WB, Sculean A, et al. Serum antibody levels against Porphyromonas gingivalis in patients with and without rheumatoid arthritis: a systematic review and meta-analysis. Clin Oral Investig 2017 ; 21 : 33–42. [PubMed] [Google Scholar]
  31. Johansson L, Sherina N, Kharlamova N, et al. Concentration of antibodies against Porphyromonas gingivalis is increased before the onset of symptoms of rheumatoid arthritis. Arthritis Res Ther 2016 ; 18 : 201. [PubMed] [Google Scholar]
  32. Marchesan JT, Gerow EA, Schaff R, et al. Porphyromonas gingivalis oral infection exacerbates the development and severity of collagen-induced arthritis. Arthritis Res Ther 2013 ; 15 : R186. [PubMed] [Google Scholar]
  33. Kaur S, Bright R, Proudman SM, et al. Does periodontal treatment influence clinical and biochemical measures for rheumatoid arthritis? A systematic review and meta-analysis. Semin Arthritis Rheum 2014 ; 44 : 113–122. [CrossRef] [PubMed] [Google Scholar]
  34. Monsarrat P, Vergnes JN, Cantagrel A, et al. Effect of periodontal treatment on the clinical parameters of patients with rheumatoid arthritis: study protocol of the randomized, controlled ESPERA trial. Trials 2013 ; 14 : 253. [Google Scholar]
  35. Ortiz P, Bissada NF, Palomo L, et al. Periodontal therapy reduces the severity of active rheumatoid arthritis in patients treated with or without tumor necrosis factor inhibitors. J Periodontol 2009 ; 80 : 535–540. [CrossRef] [PubMed] [Google Scholar]
  36. Okada M, Kobayashi T, Ito S, et al. Periodontal treatment decreases levels of antibodies to Porphyromonas gingivalis and citrulline in patients with rheumatoid arthritis and periodontitis. J Periodontol 2013 ; 84 : e74–e84. [PubMed] [Google Scholar]
  37. Moen K, Brun JG, Valen M, et al. Synovial inflammation in active rheumatoid arthritis and psoriatic arthritis facilitates trapping of a variety of oral bacterial DNAs. Clin Exp Rheumatol 2006 ; 24 : 656–663. [PubMed] [Google Scholar]
  38. Schwenzer A, Quirke AM, Marzeda AM, et al. Association of distinct fine specificities of anti-citrullinated peptide antibodies with elevated immune responses to Prevotella intermedia in a subgroup of patients with rheumatoid arthritis and periodontitis. Arthritis Rheum (Hoboken NJ) 2017 ; 69 : 2303–2313. [CrossRef] [Google Scholar]
  39. Konig MF, Abusleme L, Reinholdt J, et al. Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis. Sci Transl Med 2016; 8 : 369ra176. [CrossRef] [PubMed] [Google Scholar]
  40. Harvey GP, Fitzsimmons TR, Dhamarpatni A, et al. SSK, et al. Expression of peptidylarginine deiminase-2 and -4, citrullinated proteins and anti-citrullinated protein antibodies in human gingiva. J Periodontal Res 2013 ; 48 : 252–261. [CrossRef] [PubMed] [Google Scholar]

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