Open Access
Issue |
Med Sci (Paris)
Volume 35, Number 12, Décembre 2019
Anticorps monoclonaux en thérapeutique
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Page(s) | 926 - 936 | |
Section | De l’origine publique des anticorps monoclonaux | |
DOI | https://doi.org/10.1051/medsci/2019222 | |
Published online | 06 January 2020 |
- Köhler G, Milstein C , Continuous cultures of fused cells secreting antibody of predefined specificity. Nature. 1975;256:495–7. [Google Scholar]
- Ehrlich P, Kossel H, Wassermann A , Collected papers, vol. II, pp. 56-60. Deutsch Med Wochenschr. 1894;20:353. [CrossRef] [Google Scholar]
- Landsteiner K, van der Scheer J , On the specificity of agglutinins and precipitins. J Exp Med. 1924;40:91–107. [CrossRef] [PubMed] [Google Scholar]
- Landsteiner K, Simms S , Production of heterogenetic antibodies with mixtures of the binding part of the antigen and protein. J Exp Med. 1923;38:127–38. [CrossRef] [PubMed] [Google Scholar]
- Grabar P, Williams CW , Method permitting the combined study of the electrophoretic and the immunochemical properties of protein mixtures; application to blood serum. Biochim, Biophys Acta. 1953;10:193–4. [CrossRef] [Google Scholar]
- Heidelberger M, Pedersen KO , The molecular weight of antibodies. J Exp Med. 1937;65:393–414. [CrossRef] [PubMed] [Google Scholar]
- Tiselius A, Kabat EA , An electrophoretic study of immune sera and purified antibody preparations. J Exp Med. 1939;69:119–31. [CrossRef] [PubMed] [Google Scholar]
- McFarlane Burnet FM , A modification of Jerne’s theory of antibody production using the concept of clonal selection. Austral J Sci. 1957;20:67–9. [Google Scholar]
- Nossal GJV, Lederberg J , Antibody production by single cells. Nature. 1958;181:1419–20. [Google Scholar]
- Pauling L , A theory of the structure and process of formation of antibodies. J Am Chem Soc. 1940;62:2643–57. [Google Scholar]
- Porter RR , Separation and isolation of fractions of rabbit gamma-globulin containing the antibody and antigenic combining sites. Nature. 1958;182:670–1. [Google Scholar]
- Porter RR , The hydrolysis of rabbit γ-globulin and antibodies with crystalline papain. Biochem J. 1959;73:119–26. [CrossRef] [PubMed] [Google Scholar]
- Edelman GM, Poulik MD , Studies on structural units of the γ-globulins. J Exp Med. 1961;61–84. [Google Scholar]
- Porter RR , Symposium on basic problems in neoplastic disease. In : Gellhorn A, Hirschberg E . New York: Columbia University Press; 1962. p. 177. [Google Scholar]
- Pain RH , The molecular weights of the peptide chains of γ-globulins. Biochem J. 1963;88:234–9. [CrossRef] [PubMed] [Google Scholar]
- Edelman GM, Benacerraf B, Ovary Z, Poulik MD , Structural differences among antibodies of different specificities. Proc Natl Acad Sci USA. 1961;47:1751–8. [CrossRef] [Google Scholar]
- Fleischman JB, Porter RR, Press EM , The Arrangement of the peptide chains in γ-Globulin. Biochem J. 1963;88:220–8. [CrossRef] [PubMed] [Google Scholar]
- Edelman GM, Olins DE, Gally JA, Zinder ND , Reconstitution of immunologic activity by interaction of polypeptide chains of antibodies. Proc Natl Acad Sci USA. 1963;50:753–61. [CrossRef] [Google Scholar]
- Fougereau M, Olins DE, Edelman GM , Reconstitution of antiphage antibodies from L and H polypeptide chains and the formation of interspecies molecular hybrids. J Exp Med. 1964;120:349–58. [CrossRef] [PubMed] [Google Scholar]
- Edelman GM, Gally JA , The nature of Bence-Jones proteins - chemical similarities to polypeptide chains of myeloma globulins and normal γ-globulins. J Exp Med. 1962;116:207–27. [CrossRef] [PubMed] [Google Scholar]
- Potter M, Fahey JL, Pilgrim HI , Abnormal serum protein and bone destruction in transmissible mouse plasma cell neoplasm (multiple myeloma). Proc Soc Exp Biol Med. 1957;94:327–33. [CrossRef] [PubMed] [Google Scholar]
- Nathans D, Fahey JL, Potter M , The formation of myeloma protein by a mouse plasma cell tumor. J Exp Med. 1958;108:121–30. [CrossRef] [PubMed] [Google Scholar]
- Askonas B, Fahey JL , Formation of Bence-Jones protein and myeloma protein in vitro by the plasma-cell tumor MPC-2. Biochem J. 1961;80:261–8. [CrossRef] [PubMed] [Google Scholar]
- Merwin RM, Algire H , Induction of plasma-cell neoplasms and fibrosarcomas in BALB/c mice carrying diffusion chambers. Proc Soc Exp Biol Med. 1959;101:437–9. [CrossRef] [PubMed] [Google Scholar]
- Potter M, Robertson CL , Development of plasma-cell neoplasms in BALB/c mice after intraperitoneal injection of paraffin-oil adjuvant, heart-killed Staphylococcus mixtures. J Natl Cancer Inst. 1960;25:847–61. [CrossRef] [PubMed] [Google Scholar]
- Potter M, Boyce CR , Induction of plasma-cell neoplasms in strain BALB/c mice with mineral oil and mineral oil adjuvants. Nature. 1962;193:1086–7. [Google Scholar]
- Evans VJ, LaRock JF, Yosida TH, Potter M , A new tissue culture isolation and explantation of the P388 lymphocytic neoplasm in a chemically characterized medium. Exp Cell Res. 1963;32:212–7. [CrossRef] [PubMed] [Google Scholar]
- Laskov R, Scharff MD , Synthesis, assembly, and secretion of gamma globulin by mouse myeloma cells. I. Adaptation of the Merwin plasma cell tumor-11 to culture, cloning, and characterization of gamma globulin subunits. J Exp Med. 1970;131:515–41. [CrossRef] [PubMed] [Google Scholar]
- Horibata K, Harris AW , Mouse myelomas and lymphomas in culture. Exp Cell Res. 1970;60:61–77. [CrossRef] [PubMed] [Google Scholar]
- Bennett JC, Hood LE, Dreyer WJ, Potter W , Evidence for amino-acid sequence differences among proteins resembling the L-chain subunits of immunoglobulins. J Mol Biol. 1965;12:81–7. [Google Scholar]
- Hilschmann N, Craig LC , Amino acid sequence studies with Bence Jones proteins. Proc Natl Acad Sci USA. 1965;53:1403–9. [CrossRef] [Google Scholar]
- Koshland ME, Englberger FM , Differences in the amino acid composition of two purified antibodies from the same rabbit. Proc Natl Acad Sci USA. 1963;50:61–8. [CrossRef] [Google Scholar]
- Singer SJ, Doolittle RF , Antibody active sites and immunoglobulin molecules. Science. 1966;153:13–25. [Google Scholar]
- Edelman GM, Gally JA , Somatic recombination of duplicated genes: an hypothesis on the origin of antibody diversity. Proc Natl Acad Sci USA. 1967;57:353–8. [CrossRef] [Google Scholar]
- Brenner S, Milstein C , Origin of antibody variation. Nature. 1966;211:242–3. [Google Scholar]
- Gottlieb PD, Cunningham BA, Waxdal MJ, Konigsberg WH, Edelman GM , Variable regions of heavy and light polypeptide chains of the same γG-immunoglobulin molecule. Proc Natl Acad Sci USA. 1968;61:168–75. [CrossRef] [Google Scholar]
- Singer SJ, Thorpe NO , On the location and structure of the active sites of antibody molecules. Proc Natl Acad Sci USA. 1968;60:1371–8. [CrossRef] [Google Scholar]
- Milstein C , Linked groups of residues in immunoglobulin κ chains. Nature. 1967;216:330–2. [Google Scholar]
- Cunningham BA, Pflumm MN, Rutishauser U, Edelman GM , Subgroups of amino acid sequences in the variable regions of immunoglobulin heavy chains. Proc Natl Acad Sci USA. 1969;64:997–1003. [CrossRef] [Google Scholar]
- Dreyer WJ, Bennett CJ , The molecular basis of antibody formation: a paradox. Proc Natl Acad Sci USA. 1965;54:864–9. [CrossRef] [Google Scholar]
- Wu TT, Kabat EA , An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity. J Exp Med. 1970;132:211–50. [CrossRef] [PubMed] [Google Scholar]
- Oudin J , Allotypy of rabbit serum proteins. II. Relationships between various allotypes: their common antigenic specificity, their distribution in a sample population. Genetic implications. J Exp Med. 1960;112:125–42. [CrossRef] [PubMed] [Google Scholar]
- Oudin J , Genetic regulation of immunoglobulin synthesis. J Cell Physiol. 1966;67(suppl 1):77–108. [Google Scholar]
- Oudin J, Michel M , De la spécificité idiotypique des anticorps de lapin anti-S typhi . CR Hebd Acad Sci Seances Acad Sci Serie D. 1969;268:230–3. [Google Scholar]
- Edelman GM, Cunningham BA, Gall WE, Gottlieb PD, Rutishauser U, Waxdal MJ , The covalent structure of an entire gG immunoglobulin molecule. Proc Natl Acad Sci USA. 1969;63:78–85. [CrossRef] [Google Scholar]
- de Préval C, Pink JR, Milstein C , Variability of interchain binding of immunoglobulins. Interchain bridges of mouse IgG2a and IgG2b. Nature. 1970;228:930–2. [Google Scholar]
- Coffino P, Scharff MD , Rate of somatic mutation in immunoglobulin production by mouse myeloma cells. Proc Natl Acad Sci USA. 1971;68:219–23. [CrossRef] [Google Scholar]
- Coffino P, Laskov R, Scharff MD , Immunoglobulin production : method for quantitively detecting variant myeloma cells. Science. 1970;167:186–8. [Google Scholar]
- Secher DS, Cotton RGH, Milstein C , Spontaneous mutation in tissue culture - chemical nature of variant immunoglobulin from mutant clones of MOPC 21. FEBS Letter. 1973;37:311–6. [CrossRef] [Google Scholar]
- Periman P , IgG synthesis in hybrid cells from an antibody-producing mouse myeloma and an L cell substrain. Nature. 1970;228:1086–7. [Google Scholar]
- Coffino P, Knowles B, Nathenson SG, Scharff MD , Suppression of immunoglobulin synthesis by cellular hybridization. Nat New Biol. 1971;231:87–90. [CrossRef] [PubMed] [Google Scholar]
- Finch BW, Ephrussi B , Retention of multiple developmental potentialities by cells of a mouse testicular teratocarcinoma during prolonged culture in vitro and their extinction upon hybridization with cells of permanent lines. Proc Natl Acad Sci USA. 1967;57:615–21. [CrossRef] [Google Scholar]
- Cotton RG, Milstein C , Letter: Fusion of two immunoglobulin-producing myeloma cells. Nature. 1973;244:42–3. [Google Scholar]
- Barski G, Sorieul S, Cornefert F , Production of cells of a hybrid nature in culture in vitro of 2 cellular strains in combination. CR Hebd Seances Acad Sci. 1960;251:1825–7. [Google Scholar]
- Littlefield JW , Selection of hybrids from matings of fibroblasts in vitro and their presumed recombinants. Science. 1964;145:709–10. [Google Scholar]
- Ephrussi B, Weiss MC , Interspecific hybridization of somatic cells. Proc Natl Acad Sci USA. 1965;53:1040–2. [CrossRef] [Google Scholar]
- Okada Y , The fusion of Ehrlich’s tumor cells caused by HVJ virus in vitro. Biken J. 1958;1:103–10. [Google Scholar]
- Milstein C , From the structure of antibodies to the diversification of the immune response. Nobel lecture 8 december 1984. Biosci Rep. 1984;4:275–97 et Embo J 1985; 4 : 1083-92. [CrossRef] [PubMed] [Google Scholar]
- Milstein C , The hybridoma revolution: an offshoot of basic research. BioEssays. 1999;21:966–73. [CrossRef] [PubMed] [Google Scholar]
- Köhler G, Hengartner H, Shulman MJ , Immunoglobulin production by lymphocyte hybridomas. Eur J Immunol. 1978;8:82–8. [CrossRef] [PubMed] [Google Scholar]
- Shulman M, Wilde CD, Köhler G , A better cell line for making hybridomas secreting specific antibodies. Nature. 1978;276:269–70. [Google Scholar]
- Pontecorvo G , Production of mammalian somatic cell hybrids by means of polyethylene glycol treatment. Somat Cell Genet. 1975;1:397–400. [CrossRef] [Google Scholar]
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