Free Access
Med Sci (Paris)
Volume 32, Number 12, Décembre 2016
Page(s) 1071 - 1075
Section Nouvelles
Published online 03 January 2017
  1. Marin M, Etienne-Julan M, Piechaczyk M, Noël D. L’intégration des rétrovirus : faits et croyances. Med Sci (Paris) 1994 ; 10 : 318–324. [CrossRef] [Google Scholar]
  2. Kvaratskhelia M, Sharma A, Larue RC, et al. Molecular mechanisms of retroviral integration site selection. Nucleic Acids Res 2014 ; 42 : 10209–10225. [CrossRef] [PubMed] [Google Scholar]
  3. Gupta SS, Maetzig T, Maertens GN, et al. Bromo- and extraterminal domain chromatin regulators serve as cofactors for murine leukemia virus integration. J Virol 2013 ; 87 : 12721–12736. [CrossRef] [PubMed] [Google Scholar]
  4. Santoni FA, Hartley O, Luban J. Deciphering the code for retroviral integration target site selection. PLoS Comput Biol 2010 ; 6 : e1001008. [CrossRef] [Google Scholar]
  5. Hacein-Bey-Abina S, Pai SY, Gaspar HB, et al. A modified γ-retrovirus vector for X-linked severe combined immunodeficiency. N Engl J Med 2014 ; 371 : 1407–1417. [CrossRef] [PubMed] [Google Scholar]
  6. Suerth JD, Labenski V, Schambach A. Alpharetroviral vectors: from a cancer-causing agent to a useful tool for human gene therapy. Viruses 2014 ; 6 : 4811–4838. [CrossRef] [PubMed] [Google Scholar]
  7. Cattoglio C, Pellin D, Rizzi E, et al. High-definition mapping of retroviral integration sites identifies active regulatory elements in human multipotent hematopoietic progenitors. Blood 2010 ; 116 : 5507–5517. [CrossRef] [Google Scholar]
  8. De Ravin SS, Su L, Theobald N, et al. Enhancers are major targets for murine leukemia virus vector integration. J Virol 2014 ; 88 : 4504–4513. [CrossRef] [PubMed] [Google Scholar]
  9. LaFave MC, Varshney GK, Gildea DE, et al. MLV integration site selection is driven by strong enhancers and active promoters. Nucleic Acids Res 2014 ; 42 : 4257–4269. [CrossRef] [PubMed] [Google Scholar]
  10. Montini E, Cesana D, Schmidt M, et al. The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy. J Clin Invest 2009 ; 119 : 964–975. [CrossRef] [PubMed] [Google Scholar]
  11. Sharma A, Larue RC, Plumb MR, et al. BET proteins promote efficient murine leukemia virus integration at transcription start sites. Proc Natl Acad Sci USA 2013 ; 110 : 12036–12041. [CrossRef] [Google Scholar]
  12. De Rijck J, de Kogel C, Demeulemeester J, et al. The BET family of proteins targets Moloney murine leukemia virus integration near transcription start sites. Cell Rep 2013 ; 5 : 886–894. [CrossRef] [PubMed] [Google Scholar]
  13. Belkina AC, Denis GV. BET domain co-regulators in obesity, inflammation and cancer. Nat Rev Cancer 2012 ; 12 : 465–477. [CrossRef] [PubMed] [Google Scholar]
  14. Crowe BL, Larue RC, Yuan C, et al. Structure of the Brd4 ET domain bound to a C-terminal motif from γ-retroviral integrases reveals a conserved mechanism of interaction. Proc Natl Acad Sci USA 2016 ; 113 : 2086–2091. [CrossRef] [Google Scholar]
  15. Loven J, Hoke HA, Lin CY, et al. Selective inhibition of tumor oncogenes by disruption of super-enhancers. Cell 2013 ; 153 : 320–334. [CrossRef] [PubMed] [Google Scholar]
  16. Schambach A. Toward a safer integration profile of MLV-based retroviral vectors. Mol Ther 2014 ; 22 : 1405–1406. [CrossRef] [PubMed] [Google Scholar]
  17. Gogol-Döring A, Ammar I, Gupta S, et al. Genome-wide profiling reveals remarkable parallels between insertion site selection properties of the MLV retrovirus and the piggyBac transposon in primary human CD4+ T cells. Mol Ther 2016 ; 24 : 592–606. [CrossRef] [PubMed] [Google Scholar]

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