Free Access
Med Sci (Paris)
Volume 28, Number 3, Mars 2012
Page(s) 269 - 271
Section Nouvelles
Published online 06 April 2012
  1. Schug TT, Li X. Sirtuin 1 in lipid metabolism an obesity. Ann Med 2011 ; 43 : 198–211. [CrossRef] [PubMed] [Google Scholar]
  2. Li Y, Xu S, Giles A, et al. Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver. FASEB J 2011 ; 25 : 1664–1679. [CrossRef] [PubMed] [Google Scholar]
  3. Ramadori G, Fujikawa T, Fukuda M, et al. SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity. Cell Metab 2008 ; 12 : 78–87. [CrossRef] [Google Scholar]
  4. Purushotham A, Schug TT, Xu Q, et al. Hepatocyte-specific deletion of SIRT1 alters fattyacid metabolism and results in hepatic steatosis and inflammation. Cell Metab 2009 ; 9 : 327–338. [CrossRef] [PubMed] [Google Scholar]
  5. Chen D, Bruno J, Easlon E, et al. Tissue-specific regulation of SIRT1 by calorie restriction Genes Dev 2008 ; 22 : 1753–1757. [CrossRef] [PubMed] [Google Scholar]
  6. Wang RH, Li C, Deng CX. Liver steatosis and increased ChREBP expression in mice carrying a liver specific SIRT1 null mutation under a normal feeding condition. Int J Biol Sci 2010 ; 6 : 682–690. [CrossRef] [PubMed] [Google Scholar]
  7. Li S, Liu C, Li N, et al. Genome-wide coactivation analysis of PGC-1a identifies BAF60a as a regulator of hepatic lipid metabolism. Cell Metab 2008 ; 8 : 105–117. [CrossRef] [PubMed] [Google Scholar]
  8. Li X, Zhang S, Blander G, et al. SIRT1 deacetylates and positively regulates the nuclear receptor LXR. Mol Cell 2007 ; 28 : 91–106. [CrossRef] [PubMed] [Google Scholar]
  9. Kemper JK, Xiao Z, Ponugoti B, et al. FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states. Cell Metab 2009 ; 10 : 392–404. [CrossRef] [PubMed] [Google Scholar]
  10. Walker AK, Yang F, Jiang K, et al. Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes Dev 2010 ; 24 : 1403–1417. [CrossRef] [PubMed] [Google Scholar]
  11. Wang RH, Kim HS, Xiao C, et al. Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin résistance. J Clin Invest 2011 ; 121 : 4477–4490. [CrossRef] [PubMed] [Google Scholar]
  12. Schenk S, McCurdy CE, Philip A, et al. Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction. J Clin Invest 2011 ; 121 : 4281–4288. [CrossRef] [PubMed] [Google Scholar]
  13. Kim HS, Xiao C, Wang RH, et al. Hepatic specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis. Cell Metab 2010 ; 12 : 224–236. [CrossRef] [PubMed] [Google Scholar]
  14. Herranz D, Munoz-Martin M, Canamero M, et al. Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer. Nat Commun 2010 ; 1 : 1–8. [Google Scholar]
  15. Bosch-Presegué, Vaquero A. The dual role of sirtuins in cancer. Genes Cancer 2011 ; 2 : 648–662. [CrossRef] [PubMed] [Google Scholar]

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