Free Access
Med Sci (Paris)
Volume 25, Number 1, Janvier 2009
Page(s) 77 - 82
Section M/S revues
Published online 15 January 2009
  1. Aubin J, Jeannotte L. Implication des gènes Hox dans les processus d’organogenèse chez les mammifères. Med Sci (Paris) 2001; 17 : 54–62. [Google Scholar]
  2. Jeannotte L, Lemieux M, Charron J, et al. Specification of axial identity in the mouse: role of the Hoxa-5 (Hox1.3) gene. Genes Dev 1993; 7 : 2085–96. [Google Scholar]
  3. Aubin J, Lemieux M, Tremblay M, et al. Transcriptional interferences at the Hoxa4/Hoxa5 locus: Importance of correct Hoxa5 expression for the proper specification of the axial skeleton. Dev Dyn 1998; 212 : 141–56. [Google Scholar]
  4. Aubin J, Lemieux M, Moreau J, et al. Cooperation of Hoxa5 and Pax1 genes during formation of the pectoral girdle. Dev Biol 2002; 244 : 96–113. [Google Scholar]
  5. Rancourt DE, Tsuzuki T, Capecchi MR. Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation. Genes Dev 1995; 9 : 108–22. [Google Scholar]
  6. McIntyre DC, Rakshit S, Yallowitz AR, et al. Hox patterning of the vertebrate rib cage. Development 2007; 134 : 2981–9. [Google Scholar]
  7. Aubin J, Lemieux M, Tremblay M, et al. Early postnatal lethality in Hoxa-5 mutant mice is attributable to respiratory tract defects. Dev Biol 1997; 192 : 432–45. [Google Scholar]
  8. Kinkead R, LeBlanc M, Gulemetova R, et al. Respiratory adaptations to lung morphological defects in adult mice lacking Hoxa5 gene function. Pediatr Res 2004; 56 : 553–62. [Google Scholar]
  9. Mandeville I, Aubin J, LeBlanc M, et al. Impact of the loss of Hoxa5 function on lung alveogenesis. Am J Pathol 2006; 169 : 1312–27. [Google Scholar]
  10. Boucherat O, Franco-Montoya ML, Thibault C, et al. Gene expression profiling in lung fibroblasts reveals new players in alveolarization. Physiol Genomics 2007; 32 : 128–41. [Google Scholar]
  11. Meunier D, Aubin J, Jeannotte L. Perturbed thyroid morphology and transient hypothyroidism symptoms in Hoxa5 mutant mice. Dev Dyn 2003; 227 : 367–78. [Google Scholar]
  12. Aubin J, Déry U, Lemieux M, et al. Stomach regional specification requires Hoxa5-driven mesenchymal-epithelial signaling. Development 2002; 129 : 4075–87. [Google Scholar]
  13. Aubin J, Chailler P, Ménard D, Jeannotte L. Loss of Hoxa5 gene function in mice perturbs intestinal maturation. Am J Physiol 1999; 277 : C965–73. [Google Scholar]
  14. Garin E, Lemieux M, Coulombe Y, et al. Stromal Hoxa5 function controls the growth and differentiation of mammary alveolar epithelium. Dev Dyn 2006; 235 : 1858–71. [Google Scholar]
  15. Raman V, Martensen SA, Reisman D, et al. Compromised HOXA5 function can limit p53 expression in human breast tumours. Nature 2000; 405 : 974–8. [Google Scholar]
  16. Duriseti S, Winnard PT, Mironchik Y, et al. HOXA5 regulates hMLH1 expression in breast cancer cells. Neoplasia 2006; 8 : 250–8. [Google Scholar]
  17. Stasinopoulos IA, Mironchik Y, Raman A, et al. HOXA5-twist interaction alters p53 homeostasis in breast cancer cells. J Biol Chem 2005; 280 : 2294–9. [Google Scholar]
  18. Dik WA, Brahim W, Braun C, et al. CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes. Leukemia 2005; 19 : 1948–57. [Google Scholar]
  19. Okada Y, Jiang Q, Lemieux M, et al. Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOTIL. Nat Cell Biol 2006; 8 : 1017–24. [Google Scholar]
  20. Pearson JC, Lemons P, McGinnis W. Modulating Hox gene functions during animal body patterning. Nat Rev Genet 2005; 6 : 893–904. [Google Scholar]
  21. Kmita M, Duboule D. Organizing axes in time ans space ; 25 years of colinear tinkering. Science 2003; 301 : 331–3. [Google Scholar]
  22. Sharpe J, Nonchev S, Gould A, et al. Selectivity, sharing and competitive interactions in the regulation of Hoxb genes. EMBO J 1998; 17 : 1788–98. [Google Scholar]
  23. Yekta S, Shih IH, Bartel DP. MicroRNA-directed cleavage of HOXB8 mRNA. Science 2004; 304 : 594–6. [Google Scholar]
  24. Rinn JL, Kertesz M, Wang JK, et al. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell 2007; 129 : 1311–23. [Google Scholar]
  25. Larochelle C, Tremblay M, Bernier D, et al. Multiple cis-acting regulatory regions are required for the restricted spatio-temporal Hoxa5 expression. Dev Dyn 1999; 214 : 127–40. [Google Scholar]
  26. Joksimovic M, Jeannotte L, Tuggle CK. Dynamic expression of murine HOXA5 protein in the central nervous system. Gene Expression Patterns 2005; 5 : 792–800. [Google Scholar]
  27. Chen Y, Gorski DH. Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5. Blood 2008; 111 : 1217–26. [Google Scholar]
  28. Tuggle CK, Zakany J, Cianetti L, et al. Region-specific enhancers near two mammalian homeobox genes define adjacent rostrocaudal domains in the central nervous system. Genes Dev 1990; 4 : 180–9. [Google Scholar]
  29. Tabariès S, Lapointe J, Besch T, et al. Cdx protein interaction with Hoxa5 regulatory sequences contributes to Hoxa5 regional expression along the axial skeleton. Mol Cell Biol 2005; 25 : 1389–401. [Google Scholar]
  30. Deschamps J, Van Nes J. Developmental regulation of the Hox genes during axial morphogenesis in the mouse. Development 2005; 132 : 2931–42. [Google Scholar]
  31. Moreau J, Jeannotte L. Sequence analysis of Hoxa4-Hoxa5 intergenic region including shared regulatory elements. DNA Sequence 2002; 13 : 203–9. [Google Scholar]
  32. Packer AI, Crotty DA, Elwell VA, Wolgemuth DJ. Expression of the murine Hoxa4 gene requires both autoregulation and a conserved retinoic acid response element. Development 1998; 125 : 1991–8. [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.