Les neurones dopaminergiques greffés dans la maladie de Parkinson sont-il à leur tour atteints par le processus dégénératif ?

Faustine Lelan; Philippe Damier

doi:10.1051/medsci/200925115

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Volume 25 / No 1 (Janvier 2009)

Med Sci (Paris), 25 1 (2009) 15-16

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Issue		Med Sci (Paris) Volume 25, Number 1, Janvier 2009


Page(s)		15 - 16
Section		Nouvelles
DOI		https://doi.org/10.1051/medsci/200925115
Published online		15 January 2009

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[1] Björklund A. Dopaminergic transplants in experimental parkinsonism: cellular mechanisms of graft-induced functional recovery. Curr Opin Neurobiol 1992; 2 : 683–9. [Google Scholar]

[2] Lindvall O, Hagell P. Clinical observations after neural transplantation in Parkinson’s disease. Prog Brain Res 2000; 127 : 299–320. [Google Scholar]

[3] Freed CR, Greene PE, Breeze RE, et al. Transplantation of embryonic dopamine neurons for severe Parkinson’s disease. N Engl J Med 2001; 344 : 710–9. [Google Scholar]

[4] Olanow CW, Goetz CG, Kordower JH, et al. A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson’s disease. Ann Neurol 2003; 54 : 403–14. [Google Scholar]

[5] Kordower JH, Chu Y, Hauser RA, et al. Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson’s disease. Nat Med 2008; 14 : 504–6. [Google Scholar]

[6] Li J, Englund E, Holton JL, et al. Lewy bodies in grafted neurons in subjects with Parkinson’s disease suggest host-to-graft disease propagation. Nat Med 2008; 14 : 501–3. [Google Scholar]

[7] Mendez I, Viñuela A, Astradsson A, et al. Dopamine neurons implanted into people with Parkinson’s disease survive without pathology for 14 years. Nat Med 2008; 14 : 507–9. [Google Scholar]

[8] Corti O, Brice A. La maladie de Parkinson : que nous apprennent les gènes responsables des formes familiales ? Med Sci (Paris) 2003; 19 : 613–9. [Google Scholar]

[9] Brundin P, Li J, Holton JL, et al. Research in motion: the enigma of Parkinson’s disease pathology spread. Nat Rev Neurosci 2008; 9 : 741–5. [Google Scholar]

[10] Doucet G, Murata Y, Brundin P, et al. Host afferents into intrastriatal transplants of fetal ventral mesencephalon. Exp Neurol 1989; 106 : 1–19. [Google Scholar]