Signalisation dans les lymphocytes T : implication de canaux calciques

Marilena Djata Cabral; Bruno Gomes; Magali Savignac; Marc Moreau; Catherine Leclerc; Lucette Pelletier

doi:10.1051/medsci/2007232136

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Volume 23 / No 2 (Février 2007)

Med Sci (Paris), 23 2 (2007) 136-138

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Issue		Med Sci (Paris) Volume 23, Number 2, Février 2007


Page(s)		136 - 138
Section		Nouvelles
DOI		https://doi.org/10.1051/medsci/2007232136
Published online		15 February 2007

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[1] Cohn L, Elias JA, Chupp GL. Asthma: mechanisms of disease persistence and progression. Annu Rev Immunol 2004; 22 : 789–815. [Google Scholar]

[2] Fanger CM, Neben AL, Cahalan MD. Differential Ca²⁺ influx, KCa channel activity, and Ca²⁺ clearance distinguish Th1 and Th2 lymphocytes. J Immunol 2000; 164 : 1153–60. [Google Scholar]

[3] Ho IC, Glimcher LH. Transcription: tantalizing times for T cells. Cell 2002; 109 : S109–20. [Google Scholar]

[4] Kotturi MF, Jefferies WA. Molecular characterization of L-type calcium channel splice variants expressed in human T lymphocytes. Mol Immunol 2005; 42 : 1461–74. [Google Scholar]

[5] Navedo MF, Amberg GC, Votaw VS, Santana LF. Constitutively active L-type Ca²⁺ channels. Proc Natl Acad Sci USA 2005; 102 : 11112–7. [Google Scholar]

[6] Savignac M, Badou A, Moreau M, Leclerc C, Guery JC, Paulet P, Druet P, Ragab-Thomas J, Pelletier L. Protein kinase C-mediated calcium entry dependent upon dihydropyridine sensitive channels: a T cell receptor-coupled signaling pathway involved in IL-4 synthesis. Faseb J 2001; 15 : 1577–9. [Google Scholar]

[7] Savignac M, Gomes B, Gallard A, et al. Dihydropyridine receptors are selective markers of Th2 cells and can be targeted to prevent Th2-dependent immunopathological disorders. J Immunol 2004; 172 : 5206–12. [Google Scholar]

[8] Stokes L, Gordon J, Grafton G. Non-voltage-gated L-type Ca²⁺ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits. J Biol Chem 2004; 279 : 19566–73. [Google Scholar]