Free Access
Med Sci (Paris)
Volume 21, Number 2, Février 2005
Page(s) 150 - 155
Section M/S revues
Published online 15 February 2005
  1. Chan AC, Iwashima M, Turck CW, Weiss A. ZAP-70 : a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain. Cell 1992; 71 : 649–62. [Google Scholar]
  2. Weiss A, Littman DR. Signal transduction by lymphocyte antigen receptors. Cell 1994; 76 : 263–74. [Google Scholar]
  3. Arpaia E, Shahar M, Dadi H, et al. Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase. Cell 1994; 76 : 947–58. [Google Scholar]
  4. Elder ME, Lin D, Clever J, et al. Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase. Science 1994; 264 : 1596–9. [Google Scholar]
  5. Chan AC, Kadlecek TA, Elder ME, et al. ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency. Science 1994; 264 : 1599–601. [Google Scholar]
  6. Hivroz C, Fischer A. Immunodeficiency diseases. Multiple roles for ZAP-70. Curr Biol 1994; 4 : 731–3. [Google Scholar]
  7. Steinberg M, Swainson L, Schwarz K, et al. Retrovirus-mediated transduction of primary ZAP-70-deficient human T cells results in the selective growth advantage of gene-corrected cells : implications for gene therapy. Gene Ther 2000; 7 : 1392–40. [Google Scholar]
  8. Matsuda S, Suzuki-Fujimoto T, Minowa A, et al. Temperature-sensitive ZAP70 mutants degrading through a proteasome-independent pathway. Restoration of a kinase domain mutant by Cdc37. J Biol Chem 1999; 274 : 34515–8. [Google Scholar]
  9. Katamura K, Tai G, Tachibana T, et al. Existence of activated and memory CD4+ T cells in peripheral blood and their skin infiltration in CD8 deficiency. Clin Exp Immunol 1999; 115 : 124–30. [Google Scholar]
  10. Williams BL, Schreiber KL, Zhang W, et al. Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor : reconstitution studies in a ZAP-70-deficient Jurkat T-cell line. Mol Cell Biol 1998; 18 : 1388–99. [Google Scholar]
  11. Kadlecek TA, van Oers NS, Lefrancois L, et al. Differential requirements for ZAP-70 in TCR signaling and T cell development. J Immunol 1998; 161 : 4688–94. [Google Scholar]
  12. Meinl E, Lengenfelder D, Blank N, et al. Differential requirement of ZAP-70 for CD2-mediated activation pathways of mature human T cells. J Immunol 2000; 165 : 3578–83. [Google Scholar]
  13. Shan X, Balakir R, Criado G, et al. Zap-70-independent Ca2+ mobilization and Erk activation in Jurkat T cells in response to T-cell antigen receptor ligation. Mol Cell Biol 2001; 21 : 7137–49. [Google Scholar]
  14. Zhang W, Sloan-Lancaster J, Kitchen J, et al. LAT : the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 1998; 92 : 83–92. [Google Scholar]
  15. Wardenburg JB, Fu C, Jackman JK, et al. Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function. J Biol Chem 1996; 271 : 19641–4. [Google Scholar]
  16. Jordan MS, Singer AL, Koretzky GA. Adaptors as central mediators of signal transduction in immune cells. Nat Immunol 2003; 4 : 110–6. [Google Scholar]
  17. Goda S, Quale AC, Woods ML, et al. Control of TCR-mediated activation of beta 1 integrins by the ZAP-70 tyrosine kinase interdomain B region and the linker for activation of T cells adapter protein. J Immunol 2004; 172 : 5379–87. [Google Scholar]
  18. Blanchard N, Di Bartolo V, Hivroz C. In the immune synapse, ZAP-70 controls T cell polarization and recruitment of signaling proteins but not formation of the synaptic pattern. Immunity 2002; 17 : 389–99. [Google Scholar]
  19. van Der Merwe PA, Davis SJ. The immunological synapse : a multitasking system. Science 2002; 295 : 1479–80. [Google Scholar]
  20. Dumont C, Blanchard N, Di Bartolo V, et al. TCR/CD3 down-modulation and zeta degradation are regulated by ZAP-70. J Immunol 2002; 169 : 1705–12. [Google Scholar]
  21. Zhong L, Wu CH, Lee WH, Liu CP. Zeta-associated protein of 70 kDa (ZAP-70), but not Syk, tyrosine kinase can mediate apoptosis of T cells through the Fas/Fas ligand, caspase-8 and caspase-3 pathways. J Immunol 2004; 172 : 1472–82. [Google Scholar]
  22. Carpino N, Turner S, Mekala D, et al. Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2. Immunity 2004; 20 : 37–46. [Google Scholar]
  23. Sakaguchi N, Takahashi T, Hata H, et al. Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice. Nature 2003; 426 : 454–60. [Google Scholar]
  24. Rosenwald A, Alizadeh AA, Widhopf G, et al. Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. J Exp Med 2001; 194 : 1639–47. [Google Scholar]
  25. Orchard JA, Ibbotson RE, Davis Z, et al. ZAP-70 expression and prognosis in chronic lymphocytic leukaemia. Lancet 2004; 363 : 105–11. [Google Scholar]
  26. Chen L, Widhopf G, Huynh L, et al. Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia. Blood 2002; 100 : 4609–14. [Google Scholar]
  27. Turner M, Mee PJ, Costello PS, et al. Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk. Nature 1995; 378 : 298–302. [Google Scholar]
  28. Cheng AM, Rowley B, Pao W, et al. Syk tyrosine kinase required for mouse viability and B-cell development. Nature 1995; 378 : 303–6. [Google Scholar]
  29. Schweighoffer E, Vanes L, Mathiot A, et al. Unexpected requirement for ZAP-70 in pre-B cell development and allelic exclusion. Immunity 2003; 18 : 523–33. [Google Scholar]
  30. Elder ME, Skoda-Smith S, Kadlecek TA, et al. Distinct T cell developmental consequences in humans and mice expressing identical mutations in the DLAARN motif of ZAP-70. J Immunol 2001; 166 : 656–61. [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.