Open Access
Tableau III.
Exemples de xénobiotiques hépatotoxiques classés selon leurs mécanismes de toxicité.
| Hépatotoxicités intrinsèques | Hépatotoxicités idiosyncrasiques | |
|---|---|---|
| Immunologique | Métabolique | |
| Paracétamol | Sulfamides | Isoniazide |
| Amanitines | Phénytoïne | Kétoconazole |
| Tolcapone | Amoxicilline/acide clavulanique | Amiodarone |
| Alcaloïdes pyrrolizidiniques | Allopurinol | Phénytoïne |
| Pyrazinamide | Halothane | Diclofénac |
| Rifampicine | Minocycline, flucloxacilline | Pyrazinamide |
| Névirapine | Ximélagatran6 | Acide valproïque |
| Troglitazone | Phénothiazines | Dantrolène |
| Felbamate | Antidépresseurs tricycliques | Isotrétinoïne |
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