Lycorine induces A375 cell apoptosis. A. A375 cells analysis by flow cytometry after double Annexin V/FITC staining. B. quantitative analyses of the flow cytometry results shown in A (A375 cell apoptosis). C. Western blot of apoptosis-related proteins in lycorine-treated A375 cells. D. quantitative analysis of the Western blot images shown in C. The relative protein expression levels were normalized to the actin protein levels. ** P<0.01 compared with control group. All values are presented as means ± S.D. n = 5 for each group.