Figure 1.

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Représentation schématique de la chronologie de la production des différentes souches de souris immunodéficientes utilisées pour la transplantation de cellules ou tissus humains. BLT : bone marrow liver thymus ; CPH : cellule progénitrice humaine ; DBA : dilute brown non aguti ; FAH : fumaryl acetate hydrolase ; FRG : FAH rag gamma ; IL2Rγ : interleukin-2 receptor gamma chain ; NOD : non obese diabetic ; NSG : NOD-SCID gamma c ; Rag : recombination-activating gene ; SCID : severe combined immuno-deficiency.
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