| Issue |
Med Sci (Paris)
Volume 34, Number 10, Octobre 2018
|
|
|---|---|---|
| Page(s) | 885 - 890 | |
| Section | Forum | |
| DOI | https://doi.org/10.1051/medsci/2018222 | |
| Published online | 19 November 2018 | |
La sénescence en passe d’être vaincue ?
Chroniques génomiques
Towards success against senescence?
UMR 7268 ADÉS, Aix-Marseille, Université/EFS/CNRS ; CoReBio PACA, case 901, Parc scientifique de Luminy, 13288 Marseille Cedex 09, France
Abstract
Senescent cells are involved in many age-related diseases, and the effects of their elimination by “senolytic” drugs is an active research field. A recent paper describes a convenient murine model of induced senescence and uses it to convincingly demonstrate the positive effects of senolytics on performance and lifespan. Clinical studies have already been initiated; this approach hold promise to eventually improve human “healthspan”.
© 2018 médecine/sciences – Inserm
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