Med Sci (Paris)
Volume 34, Number 5, Mai 2018
|Page(s)||485 - 490|
|Published online||13 June 2018|
Gènes et longévité : nouvelles données, nouvelles controverses
Genes and longevity: new data, new controversies
UMR 7268 ADÉS, Aix-Marseille, Université/EFS/ CNRS ; CoReBio PACA,case 901, Parc scientifique de Luminy, 13288 Marseille Cedex 09, France
Analysis of a huge human pedigree constructed using public genealogy databases indicates that the heritability of longevity is probably lower than previously accepted (0.10 to 0.15 instead of 0.25 to 0.30). This makes the search for “longevity genes” even harder than expected; nevertheless, some significant results emerge and may eventually, after confirmation and extension, provide useful insights.
© 2018 médecine/sciences – Inserm
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