Med Sci (Paris)
Volume 33, Number 10, Octobre 2017
|Page(s)||905 - 908|
|Published online||10 October 2017|
Cancer : les trois époques de la médecine personnalisée
Cancer: three eras of personalized medicine
UMR 7268 ADÉS, Aix-Marseille, Université/EFS/CNRS, Espace éthique méditerranéen, hôpital d’adultes la Timone, 264, rue Saint-Pierre, 13385 Marseille Cedex 05, France ;
CoReBio PACA, case 901, parc scientifique de Luminy, 13288 Marseille Cedex 09, France
Since the completion of the first human DNA sequence, genomic approaches have penetrated into cancer research and therapy: first through expression profiling for diagnostic, prognostic and predictive purposes, then by sequencing of tumour DNA in order to define and apply targeted therapies. These overlapping changes occurred quite rapidly and are now overshadowed by immuno-oncology approaches that show much promise. There is however still much left to understand to make this more widely applicable, and the extreme cost of these therapies is a serious concern.
© 2017 médecine/sciences – Inserm
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