| Issue |
Med Sci (Paris)
Volume 33, Number 1, Janvier 2017
Matériaux pour la médecine de demain
|
|
|---|---|---|
| Page(s) | 105 - 108 | |
| Section | Forum | |
| DOI | https://doi.org/10.1051/medsci/20173301020 | |
| Published online | 25 January 2017 | |
Modification ciblée du génome : une nouvelle approche prometteuse
Chroniques génomiques
A new toolbox for genome editing
1
UMR 7268 ADÉS, Aix-Marseille, Université/EFS/CNRS, Espace éthique méditerranéen, hôpital d’adultes la Timone, 264, rue Saint-Pierre, 13385 Marseille Cedex 05, France
2
CoReBio PACA, case 901, parc scientifique de Luminy, 13288 Marseille Cedex 09, France
*
bertrand.jordan@univ-amu.fr ; brjordan@orange.fr
Abstract
A new approach, based on the use of peptide nucleic acid molecules to form triple helices and promote locus-specific recombination, demonstrates potential for in vivo gene correction at clinically significant levels and may provide a promising avenue for gene therapy.
© 2017 médecine/sciences – Inserm
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