| Issue |
Med Sci (Paris)
Volume 32, Number 6-7, Juin–Juillet 2016
|
|
|---|---|---|
| Page(s) | 651 - 653 | |
| Section | Forum | |
| DOI | https://doi.org/10.1051/medsci/20163206032 | |
| Published online | 12 July 2016 | |
Synthétique, vous avez dit « Synthétique » ?
Chroniques génomiques
Synthetic, really?
1
UMR 7268 ADÉS, Aix-Marseille, Université/EFS/CNRS, Espace éthique méditerranéen, hôpital d’adultesla Timone, 264, rue Saint-Pierre, 13385
Marseille Cedex 05, France
2
CoReBio PACA, case901, parc scientifique de Luminy, 13288
Marseille Cedex 09, France
*
bertrand.jordan@univ-amu.fr ; brjordan@orange.fr
Abstract
The synthesis of a minimal bacterial genome comprising only 473 genes is an impressive achievement, yet it is only a step towards a really synthetic genome based on first principles: this set of genes was derived from a larger genome by successive elimination of non-essential genes, and 149 of the final 473 genes have no specific (known) biological function. It is nevertheless an important stepping stone towards fully designed minimal genomes.
© 2016 médecine/sciences – Inserm
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