| Issue |
Med Sci (Paris)
Volume 31, Number 2, Février 2015
|
|
|---|---|---|
| Page(s) | 214 - 217 | |
| Section | Forum | |
| DOI | https://doi.org/10.1051/medsci/20153102020 | |
| Published online | 04 March 2015 | |
Recherche cibles, désespérément
Chroniques génomiques
Desperately seeking targets
UMR 7268 ADÉS, Aix-Marseille, Université/EFS/CNRS, Espace éthique méditerranéen, hôpital d’adultes la Timone, 264, rue Saint-Pierre, 13385
Marseille Cedex 05, France
;
CoReBio PACA, case 901, parc scientifique de Luminy, 13288
Marseille Cedex 09, France
*
bertrand.jordan@univ-amu.fr
**
brjordan@orange.fr
Abstract
In clinical oncology, obtaining sequence data from tumour samples has become practical in terms of logistics, turnover time and costs. The major issue now is the interpretation of this sequence to define actionable targets, i.e. genome changes that are involved in tumorogenesis and that predict the efficacy of existing and available targeted treatments. This is the focus of major efforts from public clinical centres and from companies that see it as a promising commercial activity.
© 2015 médecine/sciences – Inserm
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