| Issue |
Med Sci (Paris)
Volume 29, Number 3, Mars 2013
|
|
|---|---|---|
| Page(s) | 325 - 328 | |
| Section | Forum | |
| DOI | https://doi.org/10.1051/medsci/2013293020 | |
| Published online | 27 March 2013 | |
Chroniques génomiques
Épigénétique et résilience
Is resilience an epigenetic phenomenon?
CoReBio PACA, case 901, parc scientifique de Luminy, 13288 Marseille Cedex 9, France
Abstract
The likelihood of adult psychiatric problems is increased by childhood trauma, particularly so in carriers of certain alleles of certain genes. I discuss here a recent paper that sheds light on the mechanism of this effect, showing that specific demethylation occurring at the time of the initial trauma persists at adulthood and induces an increased reactivity to stress.
© 2013 médecine/sciences – Inserm / SRMS
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