Issue |
Med Sci (Paris)
Volume 19, Number 10, Octobre 2003
|
|
---|---|---|
Page(s) | 972 - 975 | |
Section | M/S Revues | |
DOI | https://doi.org/10.1051/medsci/20031910972 | |
Published online | 15 October 2003 |
Récepteurs de l’angiotensine dans le cerveau et adaptation au stress
Plastic expression of the brain angiotensin receptors: a molecular mechanism for stress adaptation ?
Centre de recherche en neurosciences, CHUL et Université Laval, Faculté de médecine, 2705, boulevard Laurier, Sainte-Foy, Québec, G1V 4G2 Canada
*
didier.mouginot@crchul.ulaval.ca
Nous montrons dans cet article que l’expression des récepteurs de l’angiotensine dans le cerveau est modulée lors d’un stress systémique ou psychologique. Cette plasticité a des caractéristiques distinctes selon la nature de l’agent stresseur, et pourrait contribuer à la genèse des réponses physiologiques compensatoires visant à maintenir l’intégrité de l’organisme.
Abstract
In this short review, we hypothesize that the central renin-angiotensin system might participate to the initiation of compensatory responses to a stressor agent. Regulation of the expression of the brain angiotensin receptors might constitute a primary molecular mechanism by which this protecting action would take place. We illustrate this possibility by investigating the expression of the angiotensin type 1 receptor in the hypothalamus in response to systemic and neurogenic stressors.
© 2003 médecine/sciences - Inserm / SRMS
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.