Accès gratuit
Numéro
Med Sci (Paris)
Volume 30, Numéro 2, Février 2014
Page(s) 160 - 165
Section M/S Revues
DOI https://doi.org/10.1051/medsci/20143002013
Publié en ligne 24 février 2014
  1. Hotchkiss RS, Monneret G, Payen D. Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach. Lancet Infect Dis 2013 ; 13 : 260–268. [CrossRef] [PubMed]
  2. Hotchkiss RS, Karl IE. The pathophysiology and treatment of sepsis. N Engl J Med 2003 ; 348 : 138–150. [CrossRef] [PubMed]
  3. Angus DC, van der Poll T. Severe sepsis and septic shock. N Engl J Med 2013 ; 369 : 840–851. [CrossRef] [PubMed]
  4. Meakins JL, Pietsch JB, Bubenick O, et al. Delayed hypersensitivity: indicator of acquired failure of host defenses in sepsis and trauma. Ann Surg 1977 ; 186 : 241–250. [CrossRef] [PubMed]
  5. Monneret G, Venet F, Pachot A, Lepape A. Monitoring immune dysfunctions in the septic patient: a new skin for the old ceremony. Mol Med 2008 ; 14 : 64–78. [CrossRef] [PubMed]
  6. Venet F, Lukaszewicz AC, Payen D, et al. Monitoring the immune response in sepsis: a rational approach to administration of immunoadjuvant therapies. Curr Opin Immunol 2013 ; 25 : 477–483. [CrossRef] [PubMed]
  7. Castelino DJ, McNair P, Kay TW. Lymphocytopenia in a hospital population-what does it signify? Aust NZ J Med 1997 ; 27 : 170–174. [CrossRef]
  8. Venet F, Davin F, Guignant C, et al. Early assessment of leukocyte alterations at diagnosis of septic shock. Shock 2010 ; 34 : 358–363. [CrossRef] [PubMed]
  9. Le Tulzo Y, Pangault C, Gacouin A, et al. Early circulating lymphocyte apoptosis in human septic shock is associated with poor outcome. Shock 2002 ; 18 : 487–494. [CrossRef] [PubMed]
  10. Felmet KA, Hall MW, Clark RS, et al. Prolonged lymphopenia, lymphoid depletion, and hypoprolactinemia in children with nosocomial sepsis and multiple organ failure. J Immunol 2005 ; 174 : 3765–3772. [PubMed]
  11. Inoue S, Suzuki-Utsunomiya K, Okada Y, et al. Reduction of immunocompetent T cells followed by prolonged lymphopenia in severe sepsis in the elderly. Crit Care Med 2013 ; 41 : 810–819. [CrossRef] [PubMed]
  12. Carson WF, Cavassani KA, Dou Y, Kunkel SL. Epigenetic regulation of immune cell functions during post-septic immunosuppression. Epigenetics 2011 ; 6 : 273–283. [CrossRef] [PubMed]
  13. Van de Veerdonk FL, Mouktaroudi M, Ramakers BP, et al. Deficient Candida-specific T-helper 17 response during sepsis. J Infect Dis 2012 ; 206 : 1798–1802. [CrossRef] [PubMed]
  14. Zajac AJ, Blattman JN, Murali-Krishna K, et al. Viral immune evasion due to persistence of activated T cells without effector function. J Exp Med ; 188 : 2205–2213. [CrossRef] [PubMed]
  15. Wherry EJ. T cell exhaustion. Nat Immunol 2011 ; 12 : 492–499. [CrossRef] [PubMed]
  16. Boomer JS, Shuherk-Shaffer J, Hotchkiss RS, Green JM, A prospective analysis of lymphocyte phenotype, function over the course of acute sepsis. Crit Care 2012 ; 16 : R112. [CrossRef] [PubMed]
  17. Boomer JS, To K, Chang KC, et al. Immunosuppression in patients who die of sepsis and multiple organ failure. JAMA 2011 ; 306 : 2594–2605. [CrossRef] [PubMed]
  18. Guignant C, Lepape A, Huang X, et al. Programmed death-1 levels correlate with increased mortality, nosocomial infection, immune dysfunctions in septic shock patients. Crit Care 2011 ; 15 : R99. [CrossRef] [PubMed]
  19. Christou NV, Meakins JL, Gordon J, et al. The delayed hypersensitivity response and host resistance in surgical patients. 20 years later. Ann Surg 1995 ; 222 : 534–548. [CrossRef] [PubMed]
  20. Venet F, Bohe J, Debard AL, et al. Both percentage of gammadelta T lymphocytes and CD3 expression are reduced during septic shock. Crit Care Med 2005 ; 33 : 2836–2840. [CrossRef] [PubMed]
  21. Venet F, Filipe-Santos O, Lepape A, et al. Decreased T cell repertoire diversity in sepsis: a preliminary study. Crit Care Med 2013 ; 41 : 111–119. [CrossRef] [PubMed]
  22. Monneret G, Debard AL, Venet F, et al. Marked elevation of human circulating CD4+CD25+ regulatory T cells in sepsis-induced immunoparalysis. Crit Care Med 2003 ; 31 : 2068–2071. [CrossRef] [PubMed]
  23. Venet F, Chung CS, Kherouf H, et al. Increased circulating regulatory T cells (CD4+CD25+CD127-) contribute to lymphocyte anergy in septic shock patients. Intensive Care Med 2009 ; 35 : 678–686. [CrossRef] [PubMed]
  24. Hotchkiss RS, Opal S. Immunotherapy for sepsis-a new approach against an ancient foe. N Engl J Med 2010 ; 363 : 87–89. [CrossRef] [PubMed]
  25. Docke WD, Randow F, Syrbe U, et al. Monocyte deactivation in septic patients: restoration by IFN-gamma treatment. Nat Med 1997 ; 3 : 678–681. [CrossRef] [PubMed]
  26. Meisel C, Schefold JC, Pschowski R, et al. Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial. Am J Respir Crit Care Med 2009 ; 180 : 640–648. [CrossRef] [PubMed]
  27. Mackall CL, Fry TJ, Gress RE. Harnessing the biology of IL-7 for therapeutic application. Nat Rev Immunol 2011 ; 11 : 330–342. [CrossRef] [PubMed]
  28. Lundstrom W, Fewkes NM, Mackall CL. IL-7 in human health and disease. Semin Immunol 2012 ; 24 : 218–224. [CrossRef] [PubMed]
  29. Morre M, Beq S. Interleukin-7 and immune reconstitution in cancer patients: a new paradigm for dramatically increasing overall survival. Target Oncol 2012 ; 7 : 55–68. [CrossRef] [PubMed]
  30. Unsinger J, Burnham CA, McDonough J, et al. Interleukin-7 ameliorates immune dysfunction and improves survival in a 2-hit model of fungal sepsis. J Infect Dis 2012 ; 206 : 606–616. [CrossRef] [PubMed]
  31. Unsinger J MM, Kasten KR, Hoekzema AS, et al. IL-7 Promotes T cell viability, trafficking, and functionality and improves survival in sepsis. J Immunol 2010 ; 184 : 3768–3779. [CrossRef] [PubMed]
  32. Venet F, Foray AP, Villars-Mechin A, et al. IL-7 restores lymphocyte functions in septic patients. J Immunol 2012 ; 189 : 5073–5081. [CrossRef] [PubMed]
  33. Kasten KR, Prakash PS, Unsinger J, et al. Interleukin-7 (IL-7) treatment accelerates neutrophil recruitment through gamma delta T-cell IL-17 production in a murine model of sepsis. Infect Immun 2010 ; 78 : 4714–4722. [CrossRef] [PubMed]

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