Forme soluble du récepteur de type 2 de l’IL-2 - Un candidat potentiel pour traiter l’endométriose

Khaled Khoufache; Ali Akoum

doi:10.1051/medsci/20132912012

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Volume 29 / Numéro 12 (Décembre 2013)

Med Sci (Paris), 29 12 (2013) 1097-1098

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Numéro		Med Sci (Paris) Volume 29, Numéro 12, Décembre 2013


Page(s)		1097 - 1098
Section		Nouvelles
DOI		https://doi.org/10.1051/medsci/20132912012
Publié en ligne		20 décembre 2013

Giudice LC. Clinical practice. Endometriosis. N Engl J Med 2010 ; 362 : 2389–2398. [CrossRef] [PubMed] [Google Scholar]
Farquhar C. Endometriosis. Br Med J 2007 ; 334 : 249–253. [CrossRef] [PubMed] [Google Scholar]
Akoum A, Al-Akoum M, Lemay A, et al. Imbalance in the peritoneal levels of interleukin 1 and its decoy inhibitory receptor type II in endometriosis women with infertility and pelvic pain. Fertil Steril 2008 ; 89 : 1618–1624. [CrossRef] [PubMed] [Google Scholar]
Kondera-Anasz Z, Sikora J, Mielczarek-Palacz A, et al. Concentrations of interleukin (IL)-1alpha, IL-1 soluble receptor type II (IL-1 sRII) and IL-1 receptor antagonist (IL-1 Ra) in the peritoneal fluid and serum of infertile women with endometriosis. Eur J Obstet Gynecol Reprod Biol 2005 ; 123 : 198–203. [CrossRef] [PubMed] [Google Scholar]
Akoum A, Lawson C, Herrmann-Lavoie C, et al. Imbalance in the expression of the activating type I and the inhibitory type II interleukin 1 receptors in endometriosis. Hum Reprod 2007 ; 22 : 1464–1473. [CrossRef] [PubMed] [Google Scholar]
Lawson C, Bourcier N, Al-Akoum M, et al. Abnormal interleukin 1 receptor types I and II gene expression in eutopic and ectopic endometrial tissues of women with endometriosis. J Reprod Immunol 2008 ; 77 : 75–84. [CrossRef] [PubMed] [Google Scholar]
Orlando S, Sironi M, Bianchi G, et al. Role of metalloproteases in the release of the IL-1 type II decoy receptor. J Biol Chem 1997 ; 272 : 31764–31769. [CrossRef] [PubMed] [Google Scholar]
Bossu P, Visconti U, Ruggiero P, et al. Transfected type II interleukin-1 receptor impairs responsiveness of human keratinocytes to interleukin-1. Am J Pathol 1995 ; 147 : 1852–1861. [PubMed] [Google Scholar]
Khoufache K, Kibangou Bondza P, Noria Harir, et al. Soluble human IL-1 receptor type 2 inhibits ectopic endometrial tissue implantation and growth : identification of a novel potential target for endometriosis treatment. Am J Pathol 2012 ; 181 : 1197–1205. [CrossRef] [PubMed] [Google Scholar]
Caldwell J, et al. Results of a phase 1 safety and pharmacokinetic study of interleukin-1 receptor in rheumatoid arthritis. Proc Eur League against Rheum 2002 (abstract FR10098). [Google Scholar]

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[1] Giudice LC. Clinical practice. Endometriosis. N Engl J Med 2010 ; 362 : 2389–2398. [CrossRef] [PubMed] [Google Scholar]

[2] Farquhar C. Endometriosis. Br Med J 2007 ; 334 : 249–253. [CrossRef] [PubMed] [Google Scholar]

[3] Akoum A, Al-Akoum M, Lemay A, et al. Imbalance in the peritoneal levels of interleukin 1 and its decoy inhibitory receptor type II in endometriosis women with infertility and pelvic pain. Fertil Steril 2008 ; 89 : 1618–1624. [CrossRef] [PubMed] [Google Scholar]

[4] Kondera-Anasz Z, Sikora J, Mielczarek-Palacz A, et al. Concentrations of interleukin (IL)-1alpha, IL-1 soluble receptor type II (IL-1 sRII) and IL-1 receptor antagonist (IL-1 Ra) in the peritoneal fluid and serum of infertile women with endometriosis. Eur J Obstet Gynecol Reprod Biol 2005 ; 123 : 198–203. [CrossRef] [PubMed] [Google Scholar]

[5] Akoum A, Lawson C, Herrmann-Lavoie C, et al. Imbalance in the expression of the activating type I and the inhibitory type II interleukin 1 receptors in endometriosis. Hum Reprod 2007 ; 22 : 1464–1473. [CrossRef] [PubMed] [Google Scholar]

[6] Lawson C, Bourcier N, Al-Akoum M, et al. Abnormal interleukin 1 receptor types I and II gene expression in eutopic and ectopic endometrial tissues of women with endometriosis. J Reprod Immunol 2008 ; 77 : 75–84. [CrossRef] [PubMed] [Google Scholar]

[7] Orlando S, Sironi M, Bianchi G, et al. Role of metalloproteases in the release of the IL-1 type II decoy receptor. J Biol Chem 1997 ; 272 : 31764–31769. [CrossRef] [PubMed] [Google Scholar]

[8] Bossu P, Visconti U, Ruggiero P, et al. Transfected type II interleukin-1 receptor impairs responsiveness of human keratinocytes to interleukin-1. Am J Pathol 1995 ; 147 : 1852–1861. [PubMed] [Google Scholar]

[9] Khoufache K, Kibangou Bondza P, Noria Harir, et al. Soluble human IL-1 receptor type 2 inhibits ectopic endometrial tissue implantation and growth : identification of a novel potential target for endometriosis treatment. Am J Pathol 2012 ; 181 : 1197–1205. [CrossRef] [PubMed] [Google Scholar]

[10] Caldwell J, et al. Results of a phase 1 safety and pharmacokinetic study of interleukin-1 receptor in rheumatoid arthritis. Proc Eur League against Rheum 2002 (abstract FR10098). [Google Scholar]