Nouveaux outils de cartographie génétique et génomique pour les études des traits complexes chez le rat

Dominique Gauguier; Marie-Thérèse Bihoreau

doi:10.1051/medsci/2008245545

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Volume 24 / Numéro 5 (Mai 2008)

Med Sci (Paris), 24 5 (2008) 545-547

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Numéro		Med Sci (Paris) Volume 24, Numéro 5, Mai 2008


Page(s)		545 - 547
Section		Dernière Heure
DOI		https://doi.org/10.1051/medsci/2008245545
Publié en ligne		15 mai 2008

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Gauguier D, Froguel P, Parent V, et al. Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat. Nat Genet 1996; 12 : 38–43. [Google Scholar]
Argoud K, Wilder SP, McAteer MA, et al. Genetic control of plasma lipid levels in a cross derived from normoglycaemic Brown Norway and spontaneously diabetic Goto-Kakizaki rats. Diabetologia 2006; 49 : 2679–88. [Google Scholar]
Dumas ME, Wilder SP, Bihoreau MT, et al. Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models. Nat Genet 2007; 39 : 666–72. [Google Scholar]
Gauguier D, Dumas ME. Metabonomique et cartographie génétique. Med Sci (Paris) 2007; 23 : 1091–4 [Google Scholar]
Rogner UC, Avner P. Congenic mice: cutting tools for complex immune disorders. Nat Rev Immunol 2003; 3 : 243–52. [Google Scholar]
Dardente H. Redondance génétique et synchronisation cellulaire dans les horloges circadiennes. Med Sci (Paris) 2008; 24 : 270–6. [Google Scholar]
Woon PY, Kaisaki PJ, Braganca J, et al. Aryl hydrocarbon receptor nuclear translocator-like (BMAL1) is associated with susceptibility to hypertension and type 2 diabetes. Proc Natl Acad Sci USA 2007; 104 : 14412–7. [Google Scholar]
Fearnside JF, Dumas ME, Rothwell AR, et al. Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice. PLoS One 2008; 3 : e1668. [Google Scholar]

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[1] Gauguier D. The rat as a model physiological system. In : Jorde LB, Little P, Dunn M, Subramaniam S, eds. Encyclopedia of genetics. London, UK : Wiley, 2006 : 1154–71. [Google Scholar]

[2] Saar K, Beck A, Bihoreau MT, et al. SNP and haplotype mapping for genetic analysis in the rat. Nat Genet 2008 (sous presse). [Google Scholar]

[3] Aitman T, Critser JK, Cuppen E, et al. Progress and prospects in rat genetics: a community view. Nat Genet 2008 (sous presse). [Google Scholar]

[4] Gibbs RA, Weinstock GM, Metzker ML, et al. Genome sequence of the Brown Norway rat yields insights into mammalion evolution. Nature 2004; 428 : 493–521 [Google Scholar]

[5] Valdar W, Solberg LC, Gauguier D, et al. Genome-wide genetic association of complex traits in heterogeneous stock mice. Nat Genet 2006; 38 : 879–87. [Google Scholar]

[6] Bihoreau MT, Gauguier D, Kato N, et al. A linkage map of the rat genome derived from three F2 crosses. Genome Res 1997; 7 : 434–40. [Google Scholar]

[7] Gauguier D, Froguel P, Parent V, et al. Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat. Nat Genet 1996; 12 : 38–43. [Google Scholar]

[8] Argoud K, Wilder SP, McAteer MA, et al. Genetic control of plasma lipid levels in a cross derived from normoglycaemic Brown Norway and spontaneously diabetic Goto-Kakizaki rats. Diabetologia 2006; 49 : 2679–88. [Google Scholar]

[9] Dumas ME, Wilder SP, Bihoreau MT, et al. Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models. Nat Genet 2007; 39 : 666–72. [Google Scholar]

[10] Gauguier D, Dumas ME. Metabonomique et cartographie génétique. Med Sci (Paris) 2007; 23 : 1091–4 [Google Scholar]

[11] Rogner UC, Avner P. Congenic mice: cutting tools for complex immune disorders. Nat Rev Immunol 2003; 3 : 243–52. [Google Scholar]

[12] Dardente H. Redondance génétique et synchronisation cellulaire dans les horloges circadiennes. Med Sci (Paris) 2008; 24 : 270–6. [Google Scholar]

[13] Woon PY, Kaisaki PJ, Braganca J, et al. Aryl hydrocarbon receptor nuclear translocator-like (BMAL1) is associated with susceptibility to hypertension and type 2 diabetes. Proc Natl Acad Sci USA 2007; 104 : 14412–7. [Google Scholar]

[14] Fearnside JF, Dumas ME, Rothwell AR, et al. Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice. PLoS One 2008; 3 : e1668. [Google Scholar]