Free Access
Issue
Med Sci (Paris)
Volume 23, Number 5, Mai 2007
Page(s) 470 - 472
Section Nouvelles
DOI https://doi.org/10.1051/medsci/2007235470
Published online 15 May 2007
  1. Muramatsu M, K. Kinoshita S, Fagarasan S, et al. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 2000; 102 : 553–63. [Google Scholar]
  2. Revy P, Muto T, Levy Y, et al. Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2). Cell 2000; 102 : 565–75. [Google Scholar]
  3. Reynaud CA, Aoufouchi S, Faili A, Weill JC. What role for AID: mutator, or assembler of the immunoglobulin mutasome ? Nat Immunol 2003; 4 : 631–8. [Google Scholar]
  4. Zeng X, Winter DB, Kasmer C, et al. DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes. Nat Immunol 2001; 2 : 537–41. [Google Scholar]
  5. Faili A, Aoufouchi S, Weller S, et al. DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination. J Exp Med 2004; 199 : 265–70. [Google Scholar]
  6. Delbos F, De Smet A, Faili A, et al. Contribution of DNA polymerase eta to immunoglobulin gene hypermutation in the mouse. J Exp Med 2005; 201 : 1191–6. [Google Scholar]
  7. Rada C, Di Noia JM, Neuberger MS. Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T focused phase of somatic mutation. Mol Cell 2004; 16 : 163–71. [Google Scholar]
  8. Delbos F, Aoufouchi S, Faili A, et al. DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse. J Exp Med 2007; 204 : 17–23. [Google Scholar]
  9. Friedberg EC, Wagner R, Radman M. Specialized DNA polymerases, cellular survival, and the genesis of mutations. Science 2002; 296 :1627–30. [Google Scholar]
  10. Jansen JG, Langerak P, Tsaalbi-Shtylik A, et al. Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice. J Exp Med 2006; 203 : 319–23. [Google Scholar]
  11. Diaz M, Verkoczy LK, Flajnik MF, Klinman NR. Decreased frequency of somatic hypermutation and impaired affinity maturation but intact germinal center formation in mice expressing antisense RNA to DNA polymerase zeta. J Immunol 2001; 167 : 327–35. [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.