Accès gratuit
Numéro
Med Sci (Paris)
Volume 21, Numéro 8-9, Août–Septembre 2005
Page(s) 715 - 721
Section M/S revues
DOI https://doi.org/10.1051/medsci/2005218-9715
Publié en ligne 15 août 2005
  1. Kojima M, Hosoda H, Date Y, et al. Ghrelin is a growth hormone-releasing peptide from stomach. Nature 1999, 402 : 656–60. [Google Scholar]
  2. Bowers CY, Chang J, Momany FA, et al. Effects of enkephalins and enkephalins analogs on release of pituitary hormones in vitro. In : Mc Intyre I, Szelke M, eds. Molecular endocrinology. Amsterdam : Elsevier, 1977 : 287–92. [Google Scholar]
  3. Thorner MO, Chapman IM, Gaylinn BD, et al. Growth hormone-releasing hormone and growth hormone-releasing peptide as therapeutic agents to enhance growth hormone secretion in disease and aging. Recent Prog Horm Res 1997; 52 : 215–44. [Google Scholar]
  4. Howard AD, Feighner SD, Cully DF, et al. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science 1996; 273 : 974–7. [Google Scholar]
  5. Tullin S, Hansen BS, Ankersen M, et al. Adenosine is an agonist of the growth hormone secretagogue receptor. Endocrinology 2000; 141 : 3397–402 [Google Scholar]
  6. Tomasetto C, Karam SM, Ribieras S, et al. Identification and characterization of a novel gastric peptide hormone : the motilin-related peptide. Gastroenterology 2000; 119 : 395–405. [Google Scholar]
  7. Kojima M, Hosoda H, Kaiya H, et al. Discovery of ghrelin, an endogenous ligand for the growth hormone secretagogue receptor. In : Ghigo E, ed. Ghrelin. Boston : Kluwers, 2004 : 15–25. [Google Scholar]
  8. Holst B, Cygankiewicz A, Jensen TH, et al. High constitutive signaling of the ghrelin receptor : identification of a potent inverse agonist. Mol Endocrinol 2003; 17 : 2201–10. [Google Scholar]
  9. Broglio F, Arvat E, Benso A, et al. Endocrine activities of cortistatin-14 and its interaction with GHRH and ghrelin in humans. J Clin Endocrinol Metab 2002; 87 : 3783–90. [Google Scholar]
  10. Beaumont NJ, Skinner VO, Tan TM, et al. Ghrelin can bind to a species of high density lipoprotein associated with paraoxonase. J Biol Chem 2003; 278 : 8877–80. [Google Scholar]
  11. De Vriese C, Gregoire F, Lema-Kisoka R, et al. Ghrelin degradation by serum and tissue homogenates : identification of the cleavage sites. Endocrinology 2004; 145 : 4997–5005. [Google Scholar]
  12. Bodart V, Febbraio M, Demers A, et al. CD36 mediates the cardiovascular action of growth hormone-releasing peptides in the heart. Circ Res 2002; 90 : 844–9. [Google Scholar]
  13. Frieboes RM, Antonijevic IA, Held K, et al. Hexarelin decreases slow-wave sleep and stimulates the secretion of GH, ACTH, cortisol and prolactin during sleep in healthy volunteers. Psychoneuroendocrinology 2004; 29 : 851–60. [Google Scholar]
  14. Wren AM, Seal LJ, Cohen MA, et al. Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab 2001; 86 : 5992–95. [Google Scholar]
  15. Cowley MA, Smith RG, Diano S, et al. The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron 2003; 37 : 649–61. [Google Scholar]
  16. Wortley KE, Anderson KD, Garcia K, et al. Genetic deletion of ghrelin does not decrease food intake but influences metabolic fuel preference. Proc Natl Acad Sci USA 2004; 101 : 8227–32. [Google Scholar]
  17. Tannenbaum GS, Epelbaum J, Bowers CY. Interrelationship between the novel peptide ghrelin and somatostatin/growth hormone-releasing hormone in regulation of pulsatile growth hormone secretion. Endocrinology 2003; 144 : 967–74. [Google Scholar]
  18. Nakazato M, Murakami N, Date Y, et al. A role for ghrelin in the central regulation of feeding. Nature 2001; 409 : 194–8. [Google Scholar]
  19. Tolle V, Zizzari P, Tomasetto C, et al. In vivo and in vitro effects of ghrelin/motilin-related peptide on growth hormone secretion in the rat. Neuroendocrinology 2001; 73 : 54–61. [Google Scholar]
  20. Date Y, Murakami N, Toshinai K, et al. The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats. Gastroenterology 2002; 123 : 1120–8. [Google Scholar]
  21. Tschop M, Smiley DL, Heiman ML, et al. Ghrelin induces adiposity in rodents. Nature 2000; 407 : 908–13. [Google Scholar]
  22. Thompson NM, Gill DA, Davies R, et al. Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor. Endocrinology 2004; 145 : 234–42. [Google Scholar]
  23. Sun Y, Ahmed S, Smith RG. Deletion of ghrelin impairs neither growth nor appetite. Mol Cell Biol 2003; 23 : 7973–81. [Google Scholar]
  24. Sun Y, Wang P, Zheng H, Smith RG. Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc Natl Acad Sci USA 2004; 30 : 101 : 4679–84 [Google Scholar]
  25. Masuda Y, Tanaka T, Inomata N, et al. Ghrelin stimulates gastric acid secretion and motility in rats. Biochem Biophys Res Commun 2000; 276 : 905–8. [Google Scholar]
  26. Fujino K, Inui A, Asakawa A, et al. Ghrelin induces fasted motor activity of the gastrointestinal tract in conscious fed rats. J Physiol 2003; 550 : 227–40. [Google Scholar]
  27. Trudel L, Tomasetto C, Rio MC, et al. Ghrelin/motilin-related peptide is a potent prokinetic to reverse gastric postoperative ileus in rat. Am J Physiol Gastrointest Liver Physiol 2002; 282 : G948–52. [Google Scholar]
  28. Sibilia V, Rindi G, Pagani F, et al. Ghrelin protects against ethanol-induced gastric ulcers in rats : studies on the mechanisms of action. Endocrinology 2003; 144 : 353–9. [Google Scholar]
  29. Tatsuguchi A, Miyake K, Gudis K, et al. Effect of Helicobacter pylori infection on ghrelin expression in human gastric mucosa. Am J Gastroenterol 2004; 99 : 2121–7. [Google Scholar]
  30. Zhang W, Chen M, Chen X, et al. Inhibition of pancreatic protein secretion by ghrelin in the rat. J Physiol 2001; 537 : 231–6. [Google Scholar]
  31. Arosio M, Ronchi CL, Gebbia C, et al. Stimulatory effects of ghrelin on circulating somatostatin and pancreatic polypeptide levels. J Clin Endocrinol Metab 2003; 88 : 701–4. [Google Scholar]
  32. Broglio F, Gottero C, Prodam F, et al. Non-acylated ghrelin counteracts the metabolic but not the neuroendocrine response to acylated ghrelin in humans. J Clin Endocrinol Metab 2004; 89 : 3062–5. [Google Scholar]
  33. Torsello A, Bresciani E, Rossoni G, et al. Ghrelin plays a minor role in the physiological control of cardiac function in the rat. Endocrinology 2003; 144 : 1787–92. [Google Scholar]
  34. Bisi G, Podio V, Valetto MR, et al. Cardiac effects of hexarelin in hypopituitary adults. Eur J Pharmacol 1999; 381 : 31–8. [Google Scholar]
  35. Korbonits M, Goldstone AP, Gueorguiev M, et al. Ghrelin. A hormone with multiple functions. Front Neuroendocrinol 2004; 25 : 27–68. [Google Scholar]
  36. Iglesias MJ, Pineiro R, Blanco M, et al. Growth hormone releasing peptide (ghrelin) is synthesized and secreted by cardiomyocytes. Cardiovasc Res 2004; 62 : 481–8. [Google Scholar]
  37. Tolle V, Bassant MH, Zizzari P, et al. Ultradian rhythmicity of ghrelin secretion in relation with GH, feeding behavior, and sleep-wake patterns in rats. Endocrinology 2002; 143 : 1353–61. [Google Scholar]
  38. Corbetta S, Peracchi M, Cappiello V, et al. Circulating ghrelin levels in patients with pancreatic and gastrointestinal neuroendocrine tumors : identification of one pancreatic ghrelinoma. J Clin Endocrinol Metab 2003; 88 : 3117–20. [Google Scholar]
  39. Camina JP, Carreira MC, El Messari S, et al. Desensitization and endocytosis mechanisms of ghrelin-activated growth hormone secretagogue receptor 1a. Endocrinology 2004; 145 : 930–40. [Google Scholar]
  40. Cummings DE, Frayo RS, Marmonier C, et al. Plasma ghrelin levels and hunger scores in humans initiating meals voluntarily without time- and food-related cues. Am J Physiol Endocrinol Metab 2004; 287 : E297–304. [Google Scholar]
  41. Hansen TK, Dall R, Hosoda H, et al. Weight loss increases circulating levels of ghrelin in human obesity. Clin Endocrinol 2002; 56 : 203–6 [Google Scholar]
  42. Tolle V, Kadem M, Bluet-Pajot MT, et al. Balance in ghrelin and leptin plasma levels in anorexia nervosa patients and constitutionally thin women. J Clin Endocrinol Metab 2003; 88 : 109–16. [Google Scholar]
  43. Poykko SM, Kellokoski E, Horkko S, et al. Low plasma ghrelin is associated with insulin resistance, hypertension, and the prevalence of type 2 diabetes. Diabetes 2003; 52 : 2546–53. [Google Scholar]
  44. Shiiya T, Nakazato M, Mizuta M, et al. Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion. J Clin Endocrinol Metab 2002; 87 : 240–4. [Google Scholar]
  45. Pombo M, Leal-Cerro A, Barreiro J, et al. Growth hormone releasing hexapeptide-6 (GHRP-6) test in the diagnosis of GH-deficiency. J Pediatr Endocrinol Metab 1996; 9 : 333–8. [Google Scholar]
  46. Tan TM, Vanderpump M, Khoo B, et al. Somatostatin infusion lowers plasma ghrelin without reducing appetite in adults with Prader-Willi syndrome. J Clin Endocrinol Metab 2004; 89 : 4162–5. [Google Scholar]
  47. Pantel J, Cabrol S, Nivot S, et al. Familial short stature associated with a mutation in the growth hormone secretagogue receptor (GHSR), 86th Annual meeting of the Endocrine Society. New Orleans : Endocrine Society, 2004 : O10-6 (abstract). [Google Scholar]
  48. Ariyasu H, Takaya K, Iwakura H, et al. Transgenic mice overexpressing des-acyl ghrelin show small phenotype. Endocrinology 2005; 146 : 355–64. [Google Scholar]
  49. Shuto Y, Shibasaki T, Otagiri A, et al. Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity. J Clin Invest 2002; 109 : 1429–36. [Google Scholar]
  50. Lall S, Balthasar N, Carmignac D, et al. Physiological studies of transgenic mice overexpressing growth hormone (GH) secretagogue receptor 1A in GH-releasing hormone neurons. Endocrinology 2004; 145 : 1602–11. [Google Scholar]
  51. Smith RG, Cheng K, Schoen WR, et al. A nonpeptidyl growth hormone secretagogue. Science 1993; 260 : 1640–3. [Google Scholar]

Les statistiques affichées correspondent au cumul d'une part des vues des résumés de l'article et d'autre part des vues et téléchargements de l'article plein-texte (PDF, Full-HTML, ePub... selon les formats disponibles) sur la platefome Vision4Press.

Les statistiques sont disponibles avec un délai de 48 à 96 heures et sont mises à jour quotidiennement en semaine.

Le chargement des statistiques peut être long.