Le globule rouge de culture : une nouvelle étape dans l’ingénierie cellulaire

Marie-Catherine Giarratana; Luc Douay

doi:10.1051/medsci/2005213231

Accès gratuit

Numéro		Med Sci (Paris) Volume 21, Numéro 3, Mars 2005


Page(s)		231 - 232
Section		Nouvelles
DOI		https://doi.org/10.1051/medsci/2005213231
Publié en ligne		15 mars 2005

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Neildez-Nguyen TM, Wajcman H, Marden MC, et al. Human erythroid cells produced ex vivo at large scale differentiate into red blood cells in vivo. Nat Biotechnol 2002; 20 : 467–72. [Google Scholar]
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Verfaillie CM. Soluble factor(s) produced by human bone marrow stroma increase cytokine-induced proliferation and maturation of primitive hematopoietic progenitors while preventing their terminal differentiation. Blood 1993; 82 : 2045–53. [Google Scholar]
Giarratana MC, Kobari L, Lapillonne H, et al. Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells. Nat Biotechnol 2005; 23 : 69–74. [Google Scholar]

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[1] Bessis M. Erythroblastic island, functional unity of bone marrow. Rev Hematol 1958; 13 : 8–11. [Google Scholar]

[2] Qiu LB, Dickson H, Hajibagheri N, Crocker PR. Extruded erythroblast nuclei are bound and phagocytosed by a novel macrophage receptor. Blood 1995; 85 : 1630–9. [Google Scholar]

[3] Fibach E, Manor D, Oppenheim A, Rachmilewitz EA. Proliferation and maturation of human erythroid progenitors in liquid culture. Blood 1989; 73 : 100–3. [Google Scholar]

[4] von Lindern M, Zauner W, Mellitzer G, et al. The glucocorticoid receptor cooperates with the erythropoietin receptor and c-Kit to enhance and sustain proliferation of erythroid progenitors in vitro. Blood 1999; 94 : 550–9. [Google Scholar]

[5] Malik P, Fisher TC, Barsky LL, et al. An in vitro model of human red blood cell production from hematopoietic progenitor cells. Blood 1998; 91 : 2664–71. [Google Scholar]

[6] Neildez-Nguyen TM, Wajcman H, Marden MC, et al. Human erythroid cells produced ex vivo at large scale differentiate into red blood cells in vivo. Nat Biotechnol 2002; 20 : 467–72. [Google Scholar]

[7] Ogawa M. Differentiation and proliferation of hematopoietic stem cells. Blood 1993; 81 : 2844–53. [Google Scholar]

[8] Lemischka IR. Microenvironmental regulation of hematopoietic stem cells. Stem Cells 1997; 15 (suppl 1) : 63–8. [Google Scholar]

[9] Verfaillie CM. Soluble factor(s) produced by human bone marrow stroma increase cytokine-induced proliferation and maturation of primitive hematopoietic progenitors while preventing their terminal differentiation. Blood 1993; 82 : 2045–53. [Google Scholar]

[10] Giarratana MC, Kobari L, Lapillonne H, et al. Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells. Nat Biotechnol 2005; 23 : 69–74. [Google Scholar]