Plusieurs voies pour la fibrose interstitielle pulmonaire ?

Arnold R. Brody

doi:10.1051/medsci/200117111222

Accès gratuit

Numéro		Med Sci (Paris) Volume 17, Numéro 11, Novembre 2001


Page(s)		1222 - 1223
Section		Nouvelles
DOI		https://doi.org/10.1051/medsci/200117111222
Publié en ligne		15 novembre 2001

Schwarz MI. Approach to the understanding, diagnosis, management of interstitial lung disease. In : Interstitial Lung Disease (3rd ed.), edited by Schwarz MI, King TE. St. Louis, MO : Mosby, 1998; 3030 p.
Lasky JA, Brody AR. Interstitial fibrosis and growth factors. Environ Health Perspect 2000; 108 (suppl 4) : 751–62.
Kolb M, Margetts PJ, Anthony DC, Pitossi F, Gauldie J. Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis. J Clin Invest 2001; 107: 1529–36.
Benihoud K, Yeh P, Perricaudet M. Adenovirus vectors for gene delivery. Curr Opin Biotechnol 1999; 10 : 440–7.
Sime PJ, Xing Z, Graham FL, Csaky KG, Gauldie J. Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung. J Clin Invest 1997; 100 : 768–76.
Sime PJ, Marr RA, Gauldie J, et al. Transfer of tumor necrosis factor-alpha to rat lung induces severe pulmonary inflammation and patchy interstitial fibrogenesis with induction of transforming growth factor-beta1 and myofibroblasts. Am J Pathol 1998; 153 : 825–32.
Xing Z, Tremblay GM, Sime PJ, Gauldie J. Overexpression of granulocyte-macrophage colonystimulating factor induces pulmonary granulation tissue formation and fibrosis by induction of transforming growth factorbeta 1 and myofibro-blast accumulation. Am J Pathol 1997; 150 : 59–66.
Broekelmann TJ, Limper AH, Colby TV, McDonald JA. Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis. Proc Natl Acad Sci USA 1991; 88 : 6642–6.
Liu JY, Brass DM, Hoyle GW, Brody AR. TNF-α receptor knockout mice are protected from the fibroproliferative effects of inhaled asbestos fibers. Am J Pathol 1998; 153 : 1839–47.
Ortiz LA, Lasky J, Lungarella G, et al. Upregulation of the p75 but not the p55 TNF-alpha receptor mRNA after silica and bleomycin exposure and protection from lung injury in double receptor knockout mice. Am J Respir Cell Mol Biol 1999; 20 : 825–33.
Liu JY, Sime PJ, Wu T, et al. Transforming growth factor β1 overexpression in tumor necrosis factor α receptor knockout mice induces fibroproliferative lung disease. Am J Respir Cell Mol Biol 2001; 25 : 3–7.

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[1] Schwarz MI. Approach to the understanding, diagnosis, management of interstitial lung disease. In : Interstitial Lung Disease (3rd ed.), edited by Schwarz MI, King TE. St. Louis, MO : Mosby, 1998; 3030 p.

[2] Lasky JA, Brody AR. Interstitial fibrosis and growth factors. Environ Health Perspect 2000; 108 (suppl 4) : 751–62.

[3] Kolb M, Margetts PJ, Anthony DC, Pitossi F, Gauldie J. Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis. J Clin Invest 2001; 107: 1529–36.

[4] Benihoud K, Yeh P, Perricaudet M. Adenovirus vectors for gene delivery. Curr Opin Biotechnol 1999; 10 : 440–7.

[5] Sime PJ, Xing Z, Graham FL, Csaky KG, Gauldie J. Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung. J Clin Invest 1997; 100 : 768–76.

[6] Sime PJ, Marr RA, Gauldie J, et al. Transfer of tumor necrosis factor-alpha to rat lung induces severe pulmonary inflammation and patchy interstitial fibrogenesis with induction of transforming growth factor-beta1 and myofibroblasts. Am J Pathol 1998; 153 : 825–32.

[7] Xing Z, Tremblay GM, Sime PJ, Gauldie J. Overexpression of granulocyte-macrophage colonystimulating factor induces pulmonary granulation tissue formation and fibrosis by induction of transforming growth factorbeta 1 and myofibro-blast accumulation. Am J Pathol 1997; 150 : 59–66.

[8] Broekelmann TJ, Limper AH, Colby TV, McDonald JA. Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis. Proc Natl Acad Sci USA 1991; 88 : 6642–6.

[9] Liu JY, Brass DM, Hoyle GW, Brody AR. TNF-α receptor knockout mice are protected from the fibroproliferative effects of inhaled asbestos fibers. Am J Pathol 1998; 153 : 1839–47.

[10] Ortiz LA, Lasky J, Lungarella G, et al. Upregulation of the p75 but not the p55 TNF-alpha receptor mRNA after silica and bleomycin exposure and protection from lung injury in double receptor knockout mice. Am J Respir Cell Mol Biol 1999; 20 : 825–33.

[11] Liu JY, Sime PJ, Wu T, et al. Transforming growth factor β1 overexpression in tumor necrosis factor α receptor knockout mice induces fibroproliferative lung disease. Am J Respir Cell Mol Biol 2001; 25 : 3–7.