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Tableau I.
Gènes du métabolisme réprimés ou induits par p53.
| Gènes réprimés | Gènes activés | |
|---|---|---|
| Statut redox | Cox2 [27] | Gpx1 [27] |
| Nos2 [27] | Sod2 [27] | |
| Aldh4 [27] | ||
| Ses1, 2 [3, 4] | ||
| Métabolisme des lipides | Srebp1 [17] | Lpin [15] |
| Me1, 2 [29] | Gamt [14] | |
| Crot [16] | ||
| Cpt1a [16] | ||
| Cpt1c [16] | ||
| Npc1/1 [16] | ||
| Pltp [16] | ||
| Cel [16] | ||
| Abca12 [16] | ||
| Acer2 [16] | ||
| Apobec1 [16] | ||
| Dhrs3 [16] | ||
| Glutaminolyse | Gls2 [19, 20] | |
| Glycolyse | Glut1, 4 [7] | Tigar [9] |
| Hk2 [13] | ||
| OxPhos et biogenèse des mitochondries | Pgc1a [35] | Sco2 [10] |
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