Figure 2.
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Étapes de l’angiogenèse et principaux facteurs de croissance impliqués. La figure schématise les principales étapes de l’angiogenèse; sous chaque étape sont indiqués les principaux facteurs impliqués. EGF: epithelial growth factor; bFGF: basic fibroblast growth factor; HGF: hepatocyte growth factor; IGF1: insulin-like growth factor 1; MMP: métalloprotéases de la matrice extracellulaire; PDGF: platelet derived growth factor; PLGF: placental growth factor; TGF-β: transforming growth factor β ; TNF- α: tumor necrosis factorα; VEGF: vascular endothelial growth factor (d’après [35]).
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