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Tableau III
Nombre de mutations à tester selon les prédictions in silico d’acides aminés indésirables.
| AA indésirables | Nombre de mutations proposées - Scénario |
|||||
|---|---|---|---|---|---|---|
| A | B | C | D | E | ||
| HC-CDR1 | DY | 3 | 1 | 0 | 0 | 0 |
| HC-CDR2 | DP | 3 | 2 | 2 | 2 | 1 |
| NG | 3 | 2 | 2 | 2 | 1 | |
| DT | 3 | 2 | 2 | 1 | 1 | |
| LC-CDR1 | NG | 3 | 2 | 2 | 2 | 1 |
| Nb total de variants | 20 480 | 3 240 | 1 620 | 1 080 | 320 | |
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