Tableau I.
Expression et fonctions des tétraspanines dans les carcinomes cutanés. nd : non déterminé. MRP-1 (motility related protein 1) ; BA-2/p24 (p24 antigen defined by antibody BA-2) ; PETA-3 (platelet-endothelial cell tetraspan antigen 3) ; GP27 (glycoprotein 27) ; PKCα (protein kinase C alpha) ; Jak2 (Janus kinase 2) ; Tyk2 (tyrosine kinase 2) ; STAT3 (signal transducer and activator of transcription 3).
| Carcinomes cutanés |
|||||||||
|---|---|---|---|---|---|---|---|---|---|
| Nomenclature CD | Nomenclature tétraspanine | Autres nomenclatures | Expression in situ | Impact phénotypique | Acteurs impliqués | Sources | |||
| CD9 | Tspan29 | MRP-1 ; BA-2/p24 | Forte (baso- et spinocellulaires) | nd | nd | [24] | |||
| CD151 | Tspan24 | PETA-3 ; GP27 | Augmentée (spinocellulaires) | Favorise initiation, promotion et progression des carcinomes | α6β4 ; PKCα ; Jak2 ; Tyk2 ; STAT3 | [5, 25] [27] | |||
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