Accès gratuit
Med Sci (Paris)
Volume 18, Numéro 1, Janvier 2002
Page(s) 79 - 85
Section M/S Revues : Mini-Synthéses
Publié en ligne 15 janvier 2002
  1. Werner O. On cataract in conjunction with scleroderma (translated by H. Hoehn). In : Salk D, Fujiwara Y, Martin GM eds. Werner’s syndrome and human aging,1st ed New York : Plenum Press,1985 : 1–14
  2. Epstein CJ, Martin GM, Schultz AL, Motulsky AG. Werner’s syndrome: A review of its symptomatology, natural his-tory, pathologic features, genetics and relationship to the natural aging process. Medicine 1966; 45 : 177–221.
  3. Goto M. Werner’s syndrome: From clinics to genetics. Clin Exp Rheumatoi 2000; 18 : 760–6.
  4. Goto M, Miller RW, Ishikawa Y, Sugano H. Excess of rare cancers in Werner syndrome (adult progeria). Cancer Epidemiol Biomarkers Prev 1996; 5 : 239–46.
  5. Monnat RJ Jr. Cancer patho-genesis in the human RecQ helicase deficiency syndromes. In : Goto M., Miller RW eds. From premature gray hair to helicase: Werner syndrome implications for aging and cancer. Gann Monograph on Cancer Research 2001; 49:83–94.
  6. Yu CE, Oshima J, Fu YH, et ai Positional cloning of the Werner’s syndrome gene. Science 1996; 272 : 258–62.
  7. Chakraverty RK, Hickson ID. Defending genome integrity during DNA replication: a proposed role for RecQ family helicases. BioEssays 1999; 21 : 286–94.
  8. van Brabant AJ, Stan R, Ellis NA. DNA helicases, genomic instability, and human gene-tic disease. Annu Rev Genêt 2000; 1 : 409–59.
  9. Shen JC, Loeb LA. Unwinding the molecular basis of the Werner syndrome. Mech Ageing Dev 2001; 122 : 921–44.
  10. Moser MJ, Oshima J, Monnat RJ Jr. WRN mutations in Werner syndrome. Hum Mutât 13: 271–9
  11. Goto M, Yamabe Y, Shiratori M, et ai Immunological dia-gnosis of Werner syndrome by down-regulated and truncated gene products. Hum Genêt 1999; 105 : 301–7.
  12. Moser MJ, Kamath-Loeb AS, Jacob JE, Bennett SE, Oshima J, Monnat RJ Jr. WRN helicase expression in Werner syndrome cell lines. Nucleic Acids Res 2000; 28 : 648–54.
  13. Mohaghegh P, Hickson ID. DNA helicase deficiencies associated with cancer predisposition and premature ageing disorders. Hum Mol Genet 2001; 10: 741–6.
  14. Shen JC, Loeb LA. The Werner syndrome gene: the molecular basis of RecQ helicasedeficiency diseases. Trends Genet 2000; 16 : 213–20.
  15. Fukuchi K, Martin GM, Monnat RJ Jr. Mutator phenotype of Werner syndrome is characterized by extensive deletions. Proc Natl Acad Sci USA 1989; 86 : 5893–7.
  16. Prince PR, Emond MJ, Monnat RJ Jr. Loss of Werner syndrome protein function promotes aberrant mitotic recombination. Genes Dev 2001;15 : 933–8.
  17. Thompson LH, Schild D. Homologous recombinational repair of DNA ensures mammalian chromosome stability. Mutat Res 2001; 477 : 131–53.
  18. Constantinou A, Davies AA, West SC. Branch migration and Holliday junction resolution catalyzed by activities from mammalian cells. Cell 2001; 104 : 259–68.
  19. ye L, Miki T, Nakura J, et al. Association of a polymorphic variant of the Werner helicase gene with myocardial infarction in a Japanese population. Am J Hum Genet 1997; 68 : 494–8.
  20. Castro E, Ogburn CE, Hunt KE, et al. Polymorphisms at the Werner locus: I. Newly identified polymorphisms, ethnic variability of 1367Cys/Arg, and its stability in a population of Finnish centenarians. Am J Med Genet 1999; 82 : 399–403.
  21. Castro E, Edland SD, Lee L, et al. Polymorphisms at the Werner locus: II. 1074Leu/Phe, 1367Cys/Arg, longevity, and atherosclerosis. Am J Med Genet 2000; 95 : 374–80.
  22. Moser MJ, Bigbee WL, Grant SG, et al. Genetic instability and hematologic disease risk in Werner syndrome patients and heterozygotes. Cancer Res 2000; 60 : 2492–6.
  23. Jensen RH, Bigbee WL. Direct immunofluorescence labelling provides an improved method for the glycophorin A somatic mutation assay. Cytometry 1996; 23 : 337–43.
  24. Poot M, Gollahon KA, Rabinovitch PS. Werner syndrome lymphoblastoid cells are sensitivie to camptothecin-induced apoptosis in S-phase. Hum Genet 1999; 104: 10–4.
  25. Goto M, Tanimoto K, Horiuchi Y, Sasazuki T. Family analysis of Werner’s syndrome: a survey of 42 Japanese families with a review of the literature. Clin Genet 1981; 19 : 8–15.
  26. Cerimele D, Cottoni F, Scappaticci SG, et al. 1982. High prevalence of Werner’s syndrome in Sardinia: description of six patients and estimate of the gene frequency. Hum Genet 1982; 62 : 25–30.
  27. Poot M, Yom JS, Whang SH, Kato JT, Gollahon KA, Rabinovitch PS. Werner syndrome cells are sensitive to DNA cross-linking drugs. FASEB J 2001; 15 : 1224–6.
  28. Matsumura T, Nagata M, Konishi R, Goto M. Studies of SV40-infected Werner syndrome fibroblasts. Adv Exp Med Biol 1985; 190 : 313–30.
  29. Prince PR, Ogburn CE, Moser MJ, Emond MJ, Martin GM, Monnat RJ Jr. Cell fusion corrects the 4-nitroquinoline 1-oxide sensitivity of Werner syndrome fibroblast cell lines. Hum Genet 1999; 105 : 132–8.
  30. Fry M, Loeb LA. The three faces of the WS helicase. Nat Genet 1998; 19 : 308–9.

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