Contrôler l’équilibre redox cellulaire : une fonction ubiquitaire pour la protéine prion cellulaire ?

Benoît Schneider; Mathéa Pietri; Myriam Ermonval; Sophie Mouillet-Richard; Odile Kellermann

doi:doi:10.1051/medsci/200420121

Accès gratuit

Numéro		Med Sci (Paris) Volume 20, Numéro 1, Janvier 2004


Page(s)		21 - 23
Section		Nouvelles
DOI		http://dx.doi.org/10.1051/medsci/200420121
Publié en ligne		15 January 2004

Prusiner SB. Genetic and infectious prion diseases. Arch Neurol 1993; 50 : 1129–53.
Martins VR, Mercadante AF, Cabral AL, Freitas AR, Castro RM. Insights into the physiological function of cellular prion protein. Braz J Med Biol Res 2001; 34 : 585–95.
Milhavet O, Lehmann S. Oxidative stress and the prion protein in transmissible spongiform encephalopathies. Brain Res Brain Res Rev 2002; 38 : 328–39.
Hundt C, Peyrin JM, Haik S, et al. Identification of interaction domains of the prion protein with its 37-kDa/67-kDa laminin receptor. EMBO J 2001; 20: 5876–86.
Schmitt-Ulms G, Legname G, Baldwin MA, et al. Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein. J Mol Biol 2001; 314 : 1209–25.
Mouillet-Richard S, Ermonval M, Chebassier C, et al. Signal transduction through prion protein. Science 2000; 289 : 1925–8.
Mouillet-Richard S, Mutel V, Loric S, Tournois C, Launay JM, Kellermann O. Regulation by neurotransmitter receptors of serotonergic or catecholaminergic neuronal cell differentiation. J Biol Chem 2000; 275 : 9186–92.
Schneider B, Mutel V, Pietri M, Ermonval M, Mouillet-Richard S, Kellermann O. NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells. Proc Natl Acad Sci USA 2003; 100 : 13326–31.
Sauer H, Wartenberg M, Hescheler J. Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell Physiol Biochem 2001; 11 : 173–86.
Grewal SS, York RD, Stork PJ. Extracellular-signal-regulated kinase signalling in neurons. Curr Opin Neurobiol 1999; 9 : 544–53.

[1] Prusiner SB. Genetic and infectious prion diseases. Arch Neurol 1993; 50 : 1129–53.

[2] Martins VR, Mercadante AF, Cabral AL, Freitas AR, Castro RM. Insights into the physiological function of cellular prion protein. Braz J Med Biol Res 2001; 34 : 585–95.

[3] Milhavet O, Lehmann S. Oxidative stress and the prion protein in transmissible spongiform encephalopathies. Brain Res Brain Res Rev 2002; 38 : 328–39.

[4] Hundt C, Peyrin JM, Haik S, et al. Identification of interaction domains of the prion protein with its 37-kDa/67-kDa laminin receptor. EMBO J 2001; 20: 5876–86.

[5] Schmitt-Ulms G, Legname G, Baldwin MA, et al. Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein. J Mol Biol 2001; 314 : 1209–25.

[6] Mouillet-Richard S, Ermonval M, Chebassier C, et al. Signal transduction through prion protein. Science 2000; 289 : 1925–8.

[7] Mouillet-Richard S, Mutel V, Loric S, Tournois C, Launay JM, Kellermann O. Regulation by neurotransmitter receptors of serotonergic or catecholaminergic neuronal cell differentiation. J Biol Chem 2000; 275 : 9186–92.

[8] Schneider B, Mutel V, Pietri M, Ermonval M, Mouillet-Richard S, Kellermann O. NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells. Proc Natl Acad Sci USA 2003; 100 : 13326–31.

[9] Sauer H, Wartenberg M, Hescheler J. Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell Physiol Biochem 2001; 11 : 173–86.

[10] Grewal SS, York RD, Stork PJ. Extracellular-signal-regulated kinase signalling in neurons. Curr Opin Neurobiol 1999; 9 : 544–53.

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