Fin de l’orphelinat pour les récepteurs nucléaires REVERB

Fabienne Guillaumond; Michèle Teboul

doi:doi:10.1051/medsci/20082467572

Accès gratuit

Numéro		Med Sci (Paris) Volume 24, Numéro 6-7, Juin-Juillet 2008


Page(s)		572 - 574
Section		Nouvelles
DOI		http://dx.doi.org/10.1051/medsci/20082467572
Publié en ligne		15 June 2008

Chawla A, Lazar MA. Induction of Rev-ErbA alpha, an orphan receptor encoded on the opposite strand of the alpha-thyroid hormone receptor gene, during adipocyte differentiation. J Biol Chem 1993; 268 : 16265–9.
Wang J, Lazar MA. Bifunctional role of Rev-erb-alpha in adipocyte differentiation. Mol Cell Biol 2008; 28 : 2213–20.
Downes M, Carozzi AJ, Muscat GE. Constitutive expression of the orphan receptor, Rev-erbA alpha, inhibits muscle differentiation and abrogates the expression of the myoD gene family. Mol Endocrinol 1995; 9 : 1666–78.
Burke L, Downes M, Carozzi A, et al. Transcriptional repression by the orphan steroid receptor RVR/Rev-erb beta is dependent on the signature motif and helix 5 in the E region: functional evidence for a biological role of RVR in myogenesis. Nucleic Acids Res 1996; 24 : 3481–9.
Raspé E, Duez H, Mansén A, et al. Identification of Rev-erbalpha as a physiological repressor of apoC-III gene transcription. J Lipid Res 2002; 43 : 2172–9.
Ramakrishnan SN, Lau P, Burke LJ, Muscat GE. Rev-erbbeta regulates the expression of genes involved in lipid absorption in skeletal muscle cells: evidence for cross-talk between orphan nuclear receptors and myokines. J Biol Chem 2005; 280 : 8651–9.
Teboul M, Delaunay F. Le récepteur nucléaire orphelin Rev-erbalpha oscille entre répression et activation. Med Sci (Paris) 2003; 19 : 411–3.
Dardente H. Redondance génétique et synchronisation cellulaire dans les horloges circadiennes. Med Sci (Paris) 2008; 24 : 270–6.
Guillaumond F, Dardente H, Giguère V, et al. Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors. J Biol Rhythms 2005; 20 : 391–403.
Reinking J, Lam MM, Pardee K, et al. The Drosophila nuclear receptor E75 contains heme and is gas responsive. Cell 2005; 122 : 195–207.
Yin L, Wu N, Curtin JC, et al. Rev-erb-alpha, a heme sensor that coordinates metabolic and circadian pathways. Science 2007; 318 : 1786–9.
Raghuram S, Stayrook KR, Huang P, et al. Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta. Nat Struct Mol Biol 2007; 14 : 1207–13.
Cadoudal T, Fouque F, Benelli C, Forest C. Glycéronéogenèse et PEPCK-C : cibles pharmacologiques dans le diabète de type 2. Med Sci (Paris) 2008; 24 : 407–14.
Kaasik K, Lee CC. Reciprocal regulation of haem biosynthesis and the circadian clock in mammals. Nature 2004; 430 : 467–71.

[1] Chawla A, Lazar MA. Induction of Rev-ErbA alpha, an orphan receptor encoded on the opposite strand of the alpha-thyroid hormone receptor gene, during adipocyte differentiation. J Biol Chem 1993; 268 : 16265–9.

[2] Wang J, Lazar MA. Bifunctional role of Rev-erb-alpha in adipocyte differentiation. Mol Cell Biol 2008; 28 : 2213–20.

[3] Downes M, Carozzi AJ, Muscat GE. Constitutive expression of the orphan receptor, Rev-erbA alpha, inhibits muscle differentiation and abrogates the expression of the myoD gene family. Mol Endocrinol 1995; 9 : 1666–78.

[4] Burke L, Downes M, Carozzi A, et al. Transcriptional repression by the orphan steroid receptor RVR/Rev-erb beta is dependent on the signature motif and helix 5 in the E region: functional evidence for a biological role of RVR in myogenesis. Nucleic Acids Res 1996; 24 : 3481–9.

[5] Raspé E, Duez H, Mansén A, et al. Identification of Rev-erbalpha as a physiological repressor of apoC-III gene transcription. J Lipid Res 2002; 43 : 2172–9.

[6] Ramakrishnan SN, Lau P, Burke LJ, Muscat GE. Rev-erbbeta regulates the expression of genes involved in lipid absorption in skeletal muscle cells: evidence for cross-talk between orphan nuclear receptors and myokines. J Biol Chem 2005; 280 : 8651–9.

[7] Teboul M, Delaunay F. Le récepteur nucléaire orphelin Rev-erbalpha oscille entre répression et activation. Med Sci (Paris) 2003; 19 : 411–3.

[8] Dardente H. Redondance génétique et synchronisation cellulaire dans les horloges circadiennes. Med Sci (Paris) 2008; 24 : 270–6.

[9] Guillaumond F, Dardente H, Giguère V, et al. Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors. J Biol Rhythms 2005; 20 : 391–403.

[10] Reinking J, Lam MM, Pardee K, et al. The Drosophila nuclear receptor E75 contains heme and is gas responsive. Cell 2005; 122 : 195–207.

[11] Yin L, Wu N, Curtin JC, et al. Rev-erb-alpha, a heme sensor that coordinates metabolic and circadian pathways. Science 2007; 318 : 1786–9.

[12] Raghuram S, Stayrook KR, Huang P, et al. Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta. Nat Struct Mol Biol 2007; 14 : 1207–13.

[13] Cadoudal T, Fouque F, Benelli C, Forest C. Glycéronéogenèse et PEPCK-C : cibles pharmacologiques dans le diabète de type 2. Med Sci (Paris) 2008; 24 : 407–14.

[14] Kaasik K, Lee CC. Reciprocal regulation of haem biosynthesis and the circadian clock in mammals. Nature 2004; 430 : 467–71.

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