Le foie fœtal : source incontournable de cellules souches hépatiques pour la thérapie cellulaire des maladies hépatiques ?

Anne Weber-Benarous; Jean-Étienne Allain

doi:doi:10.1051/medsci/20021810928

Accès gratuit

Numéro		Med Sci (Paris) Volume 18, Numéro 10, Octobre 2002


Page(s)		928 - 930
Section		Le Magazine : Nouvelles
DOI		http://dx.doi.org/10.1051/medsci/20021810928
Publié en ligne		15 October 2002

Alison M. Liver stem cells: a two compartment system. Curr Opin Cell Biol 1998; 10 : 710–5.
Lazaro CA, Rhim JA, Yamada Y, Fausto N. Generation of hepatocytes from oval cell precursors in culture. Cancer Res 1998; 58 : 5514–22.
Bennoun M, Rissel M, Engelhardt N, Guillouzo A, Briand P, Weber-Benarous A. Oval cell proliferation in early stages of hepatocarcinogenesis in simian virus 40 large T transgenic mice. Am J Pathol 1993; 143 : 1326–36.
Overturf K, al-Dhalimy M, Ou CN, Finegold M, Grompe M. Serial transplantation reveals the stem-cell-like regenerative potential of adult mouse hepatocytes. Am J Pathol 1997; 151 : 1273–80.
Libbrecht L, Desmet V, Van Damme B, Roskams T. Deep intralobular extension of human hepatic progenitor cells correlates with parenchymal inflammation in chronic viral hepatitis: can progenitor cells migrate? J Pathol 2000; 192 : 373–8.
Lagasse E, Connors H, Al-Dhalimy M, et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 2000; 6 : 1229–34.
Mallet VO, Mitchell C, Mezey E, et al. Bone marrow transplantation in mice leads to a minor population of hepatocytes that can be selectively amplified in vivo. Hepatology 2002; 35 : 799–04.
Peschanski M. 10 years of substitution therapy for neurodegenerative diseases using fetal neuron grafts: a positive outcome but with questions for the future. J Soc Biol 2001; 195 : 51–5.
Andreoletti M, Loux N, Vons C, et al. Engraftment of autologous retrovirally transduced hepatocytes after intraportal transplantation into nonhuman primates: implication for ex vivo gene therapy. Hum Gene Ther 2001; 12 : 169–79.
Kubota H, Reid LM. Clonogenic hepatoblasts, common precursors for hepatocytic and biliary lineages, are lacking classical major histocompatibility complex class I antigen. Proc Natl Acad Sci USA 2000; 97 : 12132–7.
Allain JE, Dagher I, Mahieu-Caputo D, et al. Immortalization of a primate bipotent epithelial liver stem cell. Proc Natl Acad Sci USA 2002; 99 : 3639–44.
Goldman JP, Blundell MP, Lopes L, Kinnon C, Di Santo JP, Thrasher AJ. Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain. Br J Haematol 1998; 103 : 335–42.

[1] Alison M. Liver stem cells: a two compartment system. Curr Opin Cell Biol 1998; 10 : 710–5.

[2] Lazaro CA, Rhim JA, Yamada Y, Fausto N. Generation of hepatocytes from oval cell precursors in culture. Cancer Res 1998; 58 : 5514–22.

[3] Bennoun M, Rissel M, Engelhardt N, Guillouzo A, Briand P, Weber-Benarous A. Oval cell proliferation in early stages of hepatocarcinogenesis in simian virus 40 large T transgenic mice. Am J Pathol 1993; 143 : 1326–36.

[4] Overturf K, al-Dhalimy M, Ou CN, Finegold M, Grompe M. Serial transplantation reveals the stem-cell-like regenerative potential of adult mouse hepatocytes. Am J Pathol 1997; 151 : 1273–80.

[5] Libbrecht L, Desmet V, Van Damme B, Roskams T. Deep intralobular extension of human hepatic progenitor cells correlates with parenchymal inflammation in chronic viral hepatitis: can progenitor cells migrate? J Pathol 2000; 192 : 373–8.

[6] Lagasse E, Connors H, Al-Dhalimy M, et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 2000; 6 : 1229–34.

[7] Mallet VO, Mitchell C, Mezey E, et al. Bone marrow transplantation in mice leads to a minor population of hepatocytes that can be selectively amplified in vivo. Hepatology 2002; 35 : 799–04.

[8] Peschanski M. 10 years of substitution therapy for neurodegenerative diseases using fetal neuron grafts: a positive outcome but with questions for the future. J Soc Biol 2001; 195 : 51–5.

[9] Andreoletti M, Loux N, Vons C, et al. Engraftment of autologous retrovirally transduced hepatocytes after intraportal transplantation into nonhuman primates: implication for ex vivo gene therapy. Hum Gene Ther 2001; 12 : 169–79.

[10] Kubota H, Reid LM. Clonogenic hepatoblasts, common precursors for hepatocytic and biliary lineages, are lacking classical major histocompatibility complex class I antigen. Proc Natl Acad Sci USA 2000; 97 : 12132–7.

[11] Allain JE, Dagher I, Mahieu-Caputo D, et al. Immortalization of a primate bipotent epithelial liver stem cell. Proc Natl Acad Sci USA 2002; 99 : 3639–44.

[12] Goldman JP, Blundell MP, Lopes L, Kinnon C, Di Santo JP, Thrasher AJ. Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain. Br J Haematol 1998; 103 : 335–42.

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