Accès gratuit
Numéro
Med Sci (Paris)
Volume 17, Numéro 12, Décembre 2001
Page(s) 1337 - 1341
Section Mini-Synthèses
DOI https://doi.org/10.1051/medsci/200117121337
Publié en ligne 15 décembre 2001
  1. Wilson CB. Immunologic basis for increased susceptibility of the neonate to infection. J Pediatr 1986; 108 : 1–12.
  2. Siegrist CA. Vaccination in the neonatal period and early infancy. Int Rev Immunol 2000; 19 : 195–219.
  3. Billingham RE, Brent L, Medawar PB. Actively acquired tolerance of foreign cells. Nature 1953; 172 : 603–6.
  4. Nossal GJ, Pike BL. Functional clonal deletion in immunological tolerance to major histocompatibility complex antigens. Proc Natl Acad Sci USA 1981; 78 : 3844–7.
  5. Feng HM, Glasebrook AL, Engers HD, Louis JA. Clonal analysis of T cell unresponsiveness to alloantigens induced by neonatal injection of F1 spleen cells into parental mice. J Immunol 1983; 131 : 2165–9.
  6. Powell TJ, Streilein JW. Neonatal tolerance induction by class II alloantigens activates IL-4-secreting, tolerogen-responsive T cells. J Immunol 1990; 144 : 854–9.
  7. Schurmans S, Heusser CH, Qin HY, et al. In vivo effects of anti-IL-4 monoclonal antibody on neonatal induction of tolerance and on an associated autoimmune syndrome. J Immunol 1990; 145 : 2465–73.
  8. Abramowicz D, Doutrelepont JM, Lambert P, Bruyns C, Goldman M. Increased expression of Ia antigens on B cells after neonatal induction of lymphoid chimerism in mice : role of interleukin 4. Eur J Immunol 1990; 20 : 469–76.
  9. Barrios C, Brawand P, Berney M, et al. Neonatal and early life immune responses to various forms of vaccine antigens qualitatively differ from adult responses : predominance of a Th2-biased pattern which persists after adult boosting. Eur J Immunol 1996; 26 : 1489–96.
  10. Sarzotti M, Robbins DS, Hoffman PM. Induction of protective CTL responses in newborn mice by a murine retrovirus. Science 1996; 271 : 1726–8.
  11. Adkins B. T-cell function in newborn mice and humans. Immunol Today 1999; 20 : 330–5.
  12. Flamand V, Donckier V, Demoor FX, et al. CD40 ligation prevents neonatal induction of transplantation tolerance. J Immunol 1998; 160 : 4666–9.
  13. Donckier V, Flamand V, Desalle F, et al. IL-12 prevents neonatal induction of transplantation tolerance in mice. Eur J Immunol 1998; 28 : 1426–30.
  14. Kovarik J, Bozzotti P, Love-Homan L, et al. CpG oligodeoxynucleotides can circumvent the Th2 polarization of neonatal responses to vaccines but may fail to fully redirect Th2 responses established by neonatal priming. J Immunol 1999; 162 : 1611–7.
  15. Martinez X, Brandt C, Saddallah F, et al. DNA immunization circumvents deficient induction of T helper type 1 and cytotoxic T lymphocyte responses in neonates and during early life. Proc Natl Acad Sci USA 1997; 94 : 8726–31.
  16. Ridge JP, Fuchs EJ F, Matzinger P. Neonatal Tolerance Revisited : Turning on Newborn T Cells with Dendritic Cells. Science 1996; 271 : 1723–6.
  17. Qureshi MH, Garvy BA. Neonatal T cells in an adult lung environment are competent to resolve Pneumocystis carinii pneumonia. J Immunol 2001; 166 : 5704–11.
  18. Wilson CB, Westall J, Johnston L, et al. Decreased production of interferon-gamma by human neonatal cells. Intrinsic and regulatory deficiencies. J Clin Invest 1986; 77 : 860–7.
  19. Melvin AJ, McGurn ME, Bort SJ, Gibson C, Lewis DB. Hypomethylation of the interferon-gamma gene correlates with its expression by primary T-lineage cells. Eur J Immunol 1995; 25 : 426–30.
  20. Hassan J , Reen DJ. Cord blood CD4+ CD45RA+ T cells achieve a lower magnitude of activation when compared with their adult counterparts. Immunology 1997; 90 : 397–401.
  21. Durandy A, De Saint B, Lisowska-Grospierre B, et al. Undetectable CD40 ligand expression on T cells and low B cell responses to CD40 binding agonists in human newborns. J Immunol 1995; 154 : 1560–8.
  22. Delespesse G, Yang LP, Ohshima Y, et al. Maturation of human neonatal CD4+ and CD8+ T lymphocytes into Th1/Th2 effectors. Vaccine 1998; 16 : 1415–9.
  23. Hunt DW, Huppertz HI, Jiang HJ, Petty RE. Studies of human cord blood dendritic cells : evidence for functional immaturity. Blood 1994; 84 : 4333–43.
  24. Goriely S, Vincart B, Stordeur P, et al. Deficient IL-12(p35) gene expression by dendritic cells derived from neonatal monocytes. J Immunol 2001; 166 : 2141–6.
  25. Lee SM, Suen Y, Chang L, et al. Decreased interleukin-12 (IL-12) from activated cord versus adult peripheral blood mononuclear cells and upregulation of interferongamma, natural killer, and lymphokine-activated killer activity by IL-12 in cord blood mononuclear cells. Blood 1996; 88 : 945–54.
  26. Marchant A, Goetghebuer T, Ota MO, et al. Newborns develop a Th1-type immune response to Mycobacterium bovis bacillus Calmette-Guerin vaccination. J Immunol 1999; 163 : 2249–55.
  27. Vekemans J, Amedei A, Ota MO, et al. Neonatal bacillus Calmette-Guérin vaccination induces adult-like IFN-gamma production by CD4+ T lymphocytes. Eur J Immunol 2001; 31 : 1531–5.

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